
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6686-70-0 |
| Catalog No. | 2A-1177753 |
| Chinese Name | Destruxin A |
| Synonyms | Destruxin A from Metarrhizium anisopliae |
| Molecular Formula | C29H47N5O7 |
| Molecular Weight | 577.71 |
| Purity | ≥98 (HPLC) |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | Destruxin A (DA) is a cyclic peptide mycotoxin derived from the entomopathogenic fungus Metarhizium anisopliae, which has insecticidal, antiviral and antiproliferative activities. |
| PubChem ID | 329798802 |
| MDL Number | MFCD01736100 |
| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CC=C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C1=O |
| InChI | 1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)/t18-,19-,20+,21-,23-,24-/m0/s1 |
| InChI Key | XIYSEKITPHTMJT-UTJJDKHZSA-N |
| NACRES Code | NA.32 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/178342_1_6686_70_0.pdf |
| Bioactivity | Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Gong L, et al. Gene expression profile of Bombyx mori hemocyte under the stress of destruxin A. PLoS One. 2014 May 6;9(5):e96170. [2]. Pal S, et al. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster. J Biol Chem. 2007 Mar 23;282(12):8969-77. [3]. Odier F, et al. In vitro effect of fungal cyclodepsipeptides on leukemic cells: study of destruxins A, B and E. Biol Cell. 1992;74(3):267-71. Chemical & Physical Properties Molecular Formula C29H47N5O7 Molecular Weight 577.71300 Exact Mass 577.34800 PSA 152.41000 LogP 1.21150 InChIKey XIYSEKITPHTMJT-OCCJOITDSA-N SMILES C=CCC1OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(C(C)CC)NC(=O)C2CCCN2C1=O Storage condition -20°C |
| Use of | Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities[1]. Properties Articles28 Name (3S,10S,13S,16S,19R)-16-[(2S)-butan-2-yl]-10,11,14-trimethyl-13-propan-2-yl-3-prop-2-enyl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone Synonym More Synonyms Destruxin A Biological Activity Description Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Gong L, et al. Gene expression profile of Bombyx mori hemocyte under the stress of destruxin A. PLoS One. 2014 May 6;9(5):e96170. [2]. Pal S, et al. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster. J Biol Chem. 2007 Mar 23;282(12):8969-77. [3]. Odier F, et al. In vitro effect of fungal cyclodepsipeptides on leukemic cells: study of destruxins A, B and E. Biol Cell. 1992;74(3):267-71. Chemical & Physical Properties Molecular Formula C29H47N5O7 Exact Mass 577.34800 PSA 152.41000 LogP 1.21150 InChIKey XIYSEKITPHTMJT-OCCJOITDSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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