![4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one structure, CAS 34523-34-7](/structures/180000/176049_1_34523_34_7.png)
CAS Number34523-34-7
Synonyms4-hydroxyphenyl methyl ketone oxime; methyl p-hydroxyphenyl ketone oxime
Molecular FormulaC8H9NO2
Molecular Weight151.16300
Density1.246g/cm3
Boiling Point294.8ºC at 760mmHg
Melting Point143 °C
AppearanceSolid;White to Orange to Green powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 34523-34-7 |
| Catalog No. | 2A-3175621 |
| Chinese Name | 4'-羟基苯乙酮肟 |
| Synonyms | 4-hydroxyphenyl methyl ketone oxime; methyl p-hydroxyphenyl ketone oxime |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16300 |
| Density | 1.246g/cm3 |
| Boiling Point | 294.8ºC at 760mmHg |
| Melting Point | 143 °C |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | 0-10°C; avoid heating |
| Application | 4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a selective cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor. It is a widely used |
| HTC | 2928000090 |
| SMILES | CC(=NO)c1ccc(O)cc1 |
| InChI | InChI=1S/C8H9NO2/c1-6(9-11)7-2-4-8(10)5-3-7/h2-5,9,11H,1H3 |
| InChI Key | BVZSQTRWIYKUSF-UHFFFAOYSA-N |
| MSDS | msds/176049_1_34523_34_7.pdf |
| Use of | 4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug[1][2]. Properties Name 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one Synonym More Synonyms 4-Hydroxyacetophenone oxime Biological Activity Description 4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90. [2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9. Chemical & Physical Properties Molecular Formula C8H9NO2 Exact Mass 151.06300 PSA 52.82000 LogP 1.59040 Index of Refraction 1.591 InChIKey BVZSQTRWIYKUSF-UHFFFAOYSA-N Safety Information Hazard Codes Xn HS Code 2928000090 Synthetic Route 4-Hydroxyacetop... CAS#:99-93-4 4-Hydroxyacetop... CAS#:34523-34-7 Literature: Baleizao, Carlos; Corma, Avelino; Garcia, Hermenegildo; Leyva, Antonio Journal of Organic Chemistry, 2004 , vol. 69, # 2 p. 439 - 446 Title/Abstract Full Text View citing articles Show Details Corma, Avelino; Garcia, Hermenegildo; Leyva, Antonio Tetrahedron, 2005 , vol. 61, # 41 p. 9848 - 9854 Acetophenone CAS#:98-86-2 4-Hydroxyacetop... CAS#:99-93-4 4-Hydroxyacetop... CAS#:34523-34-7 Literature: US6228350 B1, ; Benzamide, 4-hy... CAS#:27642-27-9 4-Hydroxyacetop... CAS#:34523-34-7 Literature: Tokmadzhyan Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749 Precursor & DownStream Precursor 3 CAS#:99-93-4 4-Hydroxyacetop... CAS#:98-86-2 Acetophenone CAS#:27642-27-9 Benzamide, 4-hy... DownStream 8 CAS#:99-93-4 4-Hydroxyacetop... CAS#:1202385-73-6 4-hydroxy-3,5-d... CAS#:103-90-2 4-Acetamidophenol CAS#:99-96-7 4-Hydroxybenzoi... |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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