CAS Number2623-33-8
Synonyms4-Acetamidophenyl acetate; Acetaminophen acetate; EINECS 220-077-6; 4-AcNHC6H4OAc; 4'-Acetoxyacetanilide; Diacetamat; P-ACETOXYACETANILIDE; MFCD00059205; N,O-Diacetyl-4-aminophenol; 4-(Acetylamino)phenyl acetate,p-Acetoxyacetanilide; 4-Acetoxyacetanilide; diacetamate
Molecular FormulaC10H11NO3
Molecular Weight193.20
Density1.2±0.1 g/cm3
Boiling Point376.4±25.0 °C at 760 mmHg
Melting Point155°C
Appearancewhite solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2623-33-8 |
| Catalog No. | 2A-3175619 |
| Chinese Name | 双醋氨酯 |
| Synonyms | 4-Acetamidophenyl acetate; Acetaminophen acetate; EINECS 220-077-6; 4-AcNHC6H4OAc; 4'-Acetoxyacetanilide; Diacetamat; P-ACETOXYACETANILIDE; MFCD00059205; N,O-Diacetyl-4-aminophenol; 4-(Acetylamino)phenyl acetate,p-Acetoxyacetanilide; 4-Acetoxyacetanilide; diacetamate |
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.20 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 376.4±25.0 °C at 760 mmHg |
| Melting Point | 155°C |
| Appearance | white solid |
| Water Solubility | Soluble in: methanol |
| Storage Condition | Sealed in a cool, dry environment. |
| Application | 4-Acetamidophenyl acetate is an impurity in acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM) and a potent inhibitor of hepatic N-acetyltransferase 2 (NAT2). |
| HTC | 2924299090 |
| SMILES | N(c1ccc(cc1)OC(=O)C)C(=O)C |
| InChI | 1S/C10H11NO3/c1-7(12)11-9-3-5-10(6-4-9)14-8(2)13/h3-6H,1-2H3,(H,11,12) |
| InChI Key | UJAOSPFULOFZRR-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | transportation |
| MSDS | msds/176047_1_2623_33_8.pdf |
| Bioactivity | 4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic drug, is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90. [2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 376.4±25.0 °C at 760 mmHg Melting Point 155°C Molecular Formula C10H11NO3 Molecular Weight 193.199 Flash Point 181.4±23.2 °C Exact Mass 193.073898 PSA 55.40000 LogP 0.60 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.561 Storage condition Refrigerator |
| Use of | 4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic drug, is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[1][2]. Properties Name (4-acetamidophenyl) acetate Synonym More Synonyms Biological Activity Description 4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic drug, is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90. [2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9. Chemical & Physical Properties Molecular Formula C10H11NO3 Exact Mass 193.073898 PSA 55.40000 Index of Refraction 1.561 Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available |
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