
CAS Number856243-80-6
SynonymsQCR-21; WP1130; (2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide; MFCD18839228; CS-0483; WP1130-Adooq Bioscience; Degrasyn
Molecular FormulaC19H18BrN3O
Molecular Weight384.27
Purity≥97 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point582.1±50.0 °C at 760 mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 856243-80-6 |
| Catalog No. | 2A-1175007 |
| Chinese Name | (2E)-3-(6-溴-2-吡啶基)-2-氰基-N-[(1S)-1-苯基丁基]-2-丙烯酰胺 |
| Synonyms | QCR-21; WP1130; (2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide; MFCD18839228; CS-0483; WP1130-Adooq Bioscience; Degrasyn |
| Molecular Formula | C19H18BrN3O |
| Molecular Weight | 384.27 |
| Purity | ≥97 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 582.1±50.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | -20℃ |
| Application | Degrasyn (WP1130) is a cell-permeable deubiquitinating enzyme (DUB) inhibitor that directly inhibits the DUB activity of USP9x, USP5, USP14 and UCH37. Degrasyn attenuates the anti-apoptotic proteins B |
| PubChem ID | 16306074 |
| MDL Number | MFCD18839228 |
| SMILES | Brc1nc(ccc1)\C=C(\C(=O)N[C@@H](CCC)c2ccccc2)/C#N |
| InChI | InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 |
| InChI Key | LIDOPKHSVQTSJY-VMEIHUARSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Transport Info | Product name: Degrasyn (WP1130) |
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| AG 490 | 133550-30-8 | 2A-1175006 |
| PH 797804 | 586379-66-0 | 2A-1175008 |
| ICG-001 | 847591-62-2 | 2A-1175010 |
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| MK 0524 | 571170-77-9 | 2A-1175015 |
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