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Miriplatin structure, CAS 141977-79-9

Miriplatin

CAS Number141977-79-9

SynonymsUNII:780F0P8N4I; UNII-780F0P8N4I; Miriplatin; Platinum(2+) tetradecanoate - (1R,2R)-1,2-cyclohexanediamine (1:2:1)

Molecular FormulaC34H68N2O4Pt

Molecular Weight763.999

Purity98%%

Density

Boiling Point

Melting Point

Flash Point

Appearancewhite solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1171123 Purity: 98%%
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Quality Control of [ 141977-79-9 ] Purity: 98%% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number141977-79-9
Catalog No.2A-1171123
Chinese Name米铂
SynonymsUNII:780F0P8N4I; UNII-780F0P8N4I; Miriplatin; Platinum(2+) tetradecanoate - (1R,2R)-1,2-cyclohexanediamine (1:2:1)
Molecular FormulaC34H68N2O4Pt
Molecular Weight763.999
Purity98%
Appearancewhite solid
Storage Conditionroom temperature
ApplicationMiriplatin is an effective chemotherapeutic agent and a type of alkylating agent.
HTC2942000000
PubChem ID14791149
InChIInChI=1S/2C14H28O2.C6H14N2.Pt/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;7-5-3-1-2-4-6(5)8;/h2*2-13H2,1H3,(H,15,16);5-6H,1-4,7-8H2;/q;;;+2/p-2/t;;5-,6-;/m..1./s1
InChI KeyBGIHRZPJIYJKAZ-BLUNCNMSSA-L
Use ofMiriplatin is a chemotherapy agent which belongs to the class of alkylating agents. Properties Name cyclohexane-1,2-diamine,platinum(4+),tetradecanoate Synonym More Synonyms Miriplatin Biological Activity Description Miriplatin is a chemotherapy agent which belongs to the class of alkylating agents. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker Research Areas >> Cancer In Vitro Miriplatin suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis[2]. References [1]. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. [2]. Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83. Chemical & Physical Properties Molecular Formula C34H68N2O4Pt Exact Mass 763.482727 PSA 132.30000 LogP 8.48790 Safety Information Hazard Codes Xi HS Code 2942000000
Transport InfoProduct name: Mi platinum
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