| Chemical & Physical Properties | |
|---|---|
| CAS Number | 915942-22-2 |
| Catalog No. | 2A-1171046 |
| Chinese Name | 马来酸来那替尼 |
| Synonyms | Target; References |
| Molecular Formula | C34H33ClN6O7 |
| Molecular Weight | 673.115 |
| Purity | 98.00% |
| Storage Condition | Inert gas protection, 2-8℃ |
| Application | Neratinib maleate (HKI-272) is an oral, irreversible, highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM respectively [1]. |
| PubChem ID | 228313259 |
| SMILES | CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C.O=C(O)C=CC(=O)O |
| InChI | InChI=1S/C30H29ClN6O3.C4H4O4/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22;5-3(6)1-2-4(7)8/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38);1-2H,(H,5,6)(H,7,8)/b9-7+;2-1- |
| InChI Key | VXZCUHNJXSIJIM-MEBGWEOYSA-N |
| Transport Info | Product Name: Neratinib Maleate |
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