Entrectinib

Name: Entrectinib
Brand: 2A Biotech
SKU: 2A-1170981

CAS Number1108743-60-7

SynonymsUNII:L5ORF0AN1I; RXDX-101; entrectinib; RXDX101; RXDX 101

Molecular FormulaC31H34F2N6O2

Molecular Weight560.638

Purity98%%

Density1.3±0.1 g/cm3

Boiling Point717.5±60.0 °C at 760 mmHg

Cat. No.: 2A-1170981 Purity: 98%%

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Quality Control of [ 1108743-60-7 ] Purity: 98%% SDS Specification MoL

Chemical & Physical Properties
CAS Number	1108743-60-7
Catalog No.	2A-1170981
Chinese Name	恩曲替尼
Synonyms	UNII:L5ORF0AN1I; RXDX-101; entrectinib; RXDX101; RXDX 101
Molecular Formula	C31H34F2N6O2
Molecular Weight	560.638
Purity	98%
Density	1.3±0.1 g/cm3
Boiling Point	717.5±60.0 °C at 760 mmHg
Storage Condition	2-8°C
Application	Entrectinib is a potent, orally active inhibitor of Trk, ROS1, and ALK; the IC50 values for inhibiting TrkA, TrkB, TrkC, ROS1, and ALK are 1, 3, 5, 12, and 7 nM, respectively.
PubChem ID	56468453
SMILES	CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1
InChI	InChI=1S/C31H34F2N6O2/c1-38-8-10-39(11-9-38)25-3-4-26(29(19-25)34-24-6-12-41-13-7-24)31(40)35-30-27-17-20(2-5-28(27)36-37-30)14-21-15-22(32)18-23(33)16-21/h2-5,15-19,24,34H,6-14H2,1H3,(H2,35,36,37,40)
InChI Key	HAYYBYPASCDWEQ-UHFFFAOYSA-N
Transport Info	Product name: Entrectinib

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