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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > (2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE
(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE structure, CAS 477575-56-7

(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE

CAS Number477575-56-7

SynonymsTCMDC-125885; PHA-665752

Molecular FormulaC32H34Cl2N4O4S

Molecular Weight641.608

Purity

Density1.4±0.1 g/cm3

Boiling Point890.2±65.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancelight yellow to light brown

EINECS

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Symbol

Signal Word

Cat. No.: 2A-1170299 Purity:
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Quality Control of [ 477575-56-7 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number477575-56-7
Catalog No.2A-1170299
Chinese NamePHA-665752
SynonymsTCMDC-125885; PHA-665752
Molecular FormulaC32H34Cl2N4O4S
Molecular Weight641.608
Density1.4±0.1 g/cm3
Boiling Point890.2±65.0 °C at 760 mmHg
Appearancelight yellow to light brown
Water SolubilityDMSO: ≥20mg/mL
Storage ConditionStore at +4°C
ApplicationPHA-665752 is an ATP-competitive c-Met selective inhibitor with an IC50 of 9 nM and is 50 times more potent than RTKs and STKs.
PubChem ID15483678
SMILESCc1[nH]c(C=C2C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1CCCC1CN1CCCC1
InChIInChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1
InChI KeyOYONTEXKYJZFHA-SSHUPFPWSA-N
Transport InfoProduct name: PHA-665752
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