
CAS Number643-12-9
Synonymscyclohexanehexol; D-Inositol; (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol; (1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexol; (1R,2R,3S,4S,5S,6S)-Cyclohexan-1,2,3,4,5,6-hexol; 1D-chiro-Inositol; cis-inositol; EINECS 211-394-0; D-Chiro-inositol(DCI); D-CHIRO-INOSITOL(DISD); MFCD00272608; D-(+)-Inositol; D-chiro-inositol
Molecular FormulaC6H12O6
Molecular Weight180.156
Purity98%
Density2.0±0.1 g/cm3
Boiling Point291.3±40.0 °C at 760 mmHg
Melting Point230 °C
Appearanceoff-white powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 643-12-9 |
| Catalog No. | 2A-1169841 |
| Chinese Name | D-手性肌醇 |
| Synonyms | cyclohexanehexol; D-Inositol; (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol; (1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexol; (1R,2R,3S,4S,5S,6S)-Cyclohexan-1,2,3,4,5,6-hexol; 1D-chiro-Inositol; cis-inositol; EINECS 211-394-0; D-Chiro-inositol(DCI); D-CHIRO-INOSITOL(DISD); MFCD00272608; D-(+)-Inositol; D-chiro-inositol |
| Molecular Formula | C6H12O6 |
| Molecular Weight | 180.156 |
| Purity | 98 |
| Density | 2.0±0.1 g/cm3 |
| Boiling Point | 291.3±40.0 °C at 760 mmHg |
| Melting Point | 230 °C |
| Appearance | off-white powder |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | D-chiro-Inositol is an inositol epimer found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans with insulin-like biological activity. D-chiro-Inositol is us |
| HTC | 29061390 |
| PubChem ID | 2958 |
| SMILES | OC1C(O)C(O)C(O)C(O)C1O |
| InChI | InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H |
| InChI Key | InChIKey=CDAISMWEOUEBRE-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3]. Related Catalog Research Areas >> Metabolic Disease References [1]. Ostlund RE Jr, et al. A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol. J Biol Chem. 1996 Apr 26;271(17):10073-8. [2]. Zhao SS, et al. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acidsecretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39(2):213-221. [3]. Cheng F, et al. chiro-Inositol Ameliorates High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance viaPKCε-PI3K/AKT Pathway. J Agric Food Chem. 2019 May 29;67(21):5957-5967. Chemical & Physical Properties Density 2.0±0.1 g/cm3 Boiling Point 291.3±40.0 °C at 760 mmHg Melting Point 230 °C Molecular Formula C6H12O6 Molecular Weight 180.156 Flash Point 143.4±21.9 °C Exact Mass 180.063385 PSA 121.38000 LogP -2.11 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.784 Storage condition Freezer |
| Use of | D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3]. Properties Name d-(+)-chiro-inositol Synonym More Synonyms D-(+)-CHIRO-INOSITOL Biological Activity Description D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3]. Related Catalog Research Areas >> Metabolic Disease References [2]. Zhao SS, et al. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acidsecretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39(2):213-221. [3]. Cheng F, et al. chiro-Inositol Ameliorates High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance viaPKCε-PI3K/AKT Pathway. J Agric Food Chem. 2019 May 29;67(21):5957-5967. Chemical & Physical Properties Molecular Formula C6H12O6 Exact Mass 180.063385 PSA 121.38000 LogP -2.11 Index of Refraction 1.784 Storage condition Freezer |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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