
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 745017-94-1 |
| Catalog No. | 2A-1169370 |
| Chinese Name | 一甲基澳瑞他汀F |
| Synonyms | MMAF; Monomethylauristatin F; Monomethyl auristatin phenylalanine; Monomethyl auristatin F |
| Molecular Formula | C39H65N5O8 |
| Molecular Weight | 731.962 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 896.8±65.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | MMAF (Monomethylauristatin F) is an anti-tubulin agent that inhibits cell division; the IC50 value for inhibiting H3397 cell growth is 105 nM. |
| PubChem ID | 15410802 |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1ccccc1)C(=O)O)OC)N(C)C(=O)C(NC(=O)C(NC)C(C)C)C(C)C |
| InChI | InChI=1S/C39H65N5O8/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-17-14-13-15-18-27/h13-15,17-18,23-26,28-30,32-35,40H,12,16,19-22H2,1-11H3,(H,41,46)(H,42,47)(H,49,50)/t25-,26+,28-,29-,30+,32-,33-,34-,35+/m0/s1 |
| InChI Key | MFRNYXJJRJQHNW-UHFFFAOYSA-N |
| Transport Info | Product name: MMAF |
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