CAS Number57-68-1
Synonymssulfadimidine; MFCD00006066; 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide; EINECS 200-346-4
Molecular FormulaC12H14N4O2S
Molecular Weight278.33
Purity99.0-101.0 (on dried basis)%
Density1.4±0.1 g/cm3
Boiling Point526.2±52.0 °C at 760 mmHg
Melting Point197 °C
Appearancepowder or crystals
EINECS200-346-4
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57-68-1 |
| Catalog No. | 2A-9016754 |
| Chinese Name | 磺胺二甲嘧啶 |
| Synonyms | sulfadimidine; MFCD00006066; 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide; EINECS 200-346-4 |
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.33 |
| Purity | 99.0-101.0 (on dried basis) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 526.2±52.0 °C at 760 mmHg |
| Melting Point | 197 °C |
| Appearance | powder or crystals |
| Water Solubility | 150mg/100mL (29 ºC) |
| Storage Condition | This product should be sealed and stored in a cool |
| Application | Sulfamethazine is a sulfonamide antibiotic. |
| EINECS | 200-346-4 |
| HTC | 2935009090 |
| PubChem ID | 24899686 |
| MDL Number | MFCD00006066 |
| SMILES | Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 |
| InChI | 1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) |
| InChI Key | ASWVTGNCAZCNNR-UHFFFAOYSA-N |
| Beilstein/REAXYS | 261304 |
| NACRES Code | NA.85 |
| UNSPSC | 51284910 |
| Safety Description | S24/25 |
| MSDS | msds/16754_1_57_68_1.pdf |
| Bioactivity | Sulfamethazine is a sulfonamide antibacterial.Target: AntibacterialSulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis [1, 2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Perez, S., P. Eichhorn, and D.S. Aga, Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem, 2005. 24(6): p. 1361-7. [2]. Kaniou, S., et al., Photocatalytic oxidation of sulfamethazine. Chemosphere, 2005. 60(3): p. 372-80. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 526.2±52.0 °C at 760 mmHg Melting Point 197 °C Molecular Formula C12H14N4O2S Molecular Weight 278.330 Flash Point 272.1±30.7 °C Exact Mass 278.083740 PSA 106.35000 LogP 0.80 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.644 InChIKey ASWVTGNCAZCNNR-UHFFFAOYSA-N SMILES Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 Storage condition 2-8°C Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. Water Solubility 150mg/100mL (29 ºC) |
| Use of | Sulfamethazine is a sulfonamide antibacterial.Target: AntibacterialSulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis [1, 2]. Properties Articles77 Name sulfamethazine Synonym More Synonyms Sulfamethazine Biological Activity Description Sulfamethazine is a sulfonamide antibacterial.Target: AntibacterialSulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis [1, 2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Perez, S., P. Eichhorn, and D.S. Aga, Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem, 2005. 24(6): p. 1361-7. [2]. Kaniou, S., et al., Photocatalytic oxidation of sulfamethazine. Chemosphere, 2005. 60(3): p. 372-80. Chemical & Physical Properties Molecular Formula C12H14N4O2S Exact Mass 278.083740 PSA 106.35000 Index of Refraction 1.644 InChIKey ASWVTGNCAZCNNR-UHFFFAOYSA-N Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods |
| Inspection | M. Imported goods inspection |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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