CAS Number464-45-9
SynonymsL-BORNEOL; l-2-Bornanol; Borneol; endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol; endo-2-hydroxycamphane; 2-Camphanol; L(-)-Borneol; (1S,2R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol; [(1s)-endo]-(-)-borneol; EINECS 207-353-1; (1S-endo)-1,7,7-Trimethylbicyclo(2.2.1)heptan-2-ol; (-)-Borneol; (−)-Borneol; FEMA 2157; (1S)-endo-(-)-Borneol; 2-bornanol; Bornan-2-ol; MFCD00003759; (？)-Borneol; endo-2-Bornanol; Linderol; endo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol; endo-2-camphanol; ngaicamphor; bornel
Molecular FormulaC10H18O
Molecular Weight154.25
Purity97%
Density1.0±0.1 g/cm3
Boiling Point210 °C (lit.)
Melting Point206-208 °C (lit.)
Appearancesolid
EINECS207-353-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 464-45-9 |
| Catalog No. | 2A-0202026 |
| Chinese Name | 左旋龙脑 |
| Synonyms | L-BORNEOL; l-2-Bornanol; Borneol; endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol; endo-2-hydroxycamphane; 2-Camphanol; L(-)-Borneol; (1S,2R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol; [(1s)-endo]-(-)-borneol; EINECS 207-353-1; (1S-endo)-1,7,7-Trimethylbicyclo(2.2.1)heptan-2-ol; (-)-Borneol; (−)-Borneol; FEMA 2157; (1S)-endo-(-)-Borneol; 2-bornanol; Bornan-2-ol; MFCD00003759; (？)-Borneol; endo-2-Bornanol; Linderol; endo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol; endo-2-camphanol; ngaicamphor; bornel |
| Molecular Formula | C10H18O |
| Molecular Weight | 154.25 |
| Purity | 97 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 210 °C (lit.) |
| Melting Point | 206-208 °C (lit.) |
| Appearance | solid |
| Water Solubility | INSOLUBLE |
| Storage Condition | Store in a sealed container in a ventilated and dr |
| Packaging | III |
| Application | (-)-Borneol has a highly potent positive modulatory effect on GABA receptors with an EC50 value of 237 μM. |
| EINECS | 207-353-1 |
| HTC | 29061900 |
| UN(IATA) | 1312 |
| PubChem ID | 24848391 |
| MDL Number | MFCD00003759 |
| SMILES | [H][C@]12CC[C@](C)([C@H](O)C1)C2(C)C |
| InChI | 1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1 |
| InChI Key | DTGKSKDOIYIVQL-QXFUBDJGSA-N |
| Beilstein/REAXYS | 2038053 |
| NACRES Code | NA.22 |
| UNSPSC | 12352212 |
| Hazard Symbols | 4.1 |
| Risk Codes | R24/25;R26;R48/25 |
| Safety Description | S28A;S36/37;S45 |
| MSDS | msds/16540_1_464_45_9.pdf |
| Bioactivity | (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Research Areas >> Neurological Disease Natural Products >> Terpenoids and Glycosides Target EC50: 237 μM (GABA receptor)[1] In Vitro (-)-Borneol is an enantiomer of (+)-Borneol. (+)-Borneol is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM. At high concentrations (>1.5 mM), (-)-Borneol directly activates GABAA receptors producing 84% of the maximal GABA response indicative of a weak partial agonist action. (-)-Borneol produces dose-dependent positive modulation of the Cl- conductance generated by extremely low dose GABA at α1β2γ2L GABAA receptors[1]. References [1]. IGranger RE, et al. (+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinantalpha1beta2gamma2L GABA(A) receptors. Biochem Pharmacol. 2005 Apr 1;69(7):1101-11. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 212.0±0.0 °C at 760 mmHg Melting Point 206-209 °C Molecular Formula C10H18O Molecular Weight 154.249 Flash Point 65.6±0.0 °C Exact Mass 154.135757 PSA 20.23000 LogP 2.71 Vapour density 5.31 (vs air) Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.502 Water Solubility INSOLUBLE |
| Use of | (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM. Properties Articles30 Name (-)-borneol Synonym More Synonyms (-)-Borneol Biological Activity Description (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Research Areas >> Neurological Disease Natural Products >> Terpenoids and Glycosides EC50: 237 μM (GABA receptor)[1] References Chemical & Physical Properties Molecular Formula C10H18O Exact Mass 154.135757 PSA 20.23000 Vapour density 5.31 (vs air) Index of Refraction 1.502 Water Solubility INSOLUBLE |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Dangerous Regulations for land transport: 1312 International Dangerous Regulations for sea transport: 1312 International Dangerous Regulations for air transport: 1312 14.2 Names specified by the United Nations (UN) European Land Transport Danger Regulations: BORNEOL IMDG: BORNEOL International Air Transport Danger Regulations: Borneol 14.3 Transport hazard categories European Land Transport Danger Regulations: 4.1 International Maritime Transport Danger Regulations: 4.1 International Air Transport Danger Regulations: 4.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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