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2',3',5'-Triacetyluridine structure, CAS 4105-38-8

2',3',5'-Triacetyluridine

CAS Number4105-38-8

Synonyms2',3',5-TRI-ACETYLURIDINE; EINECS 223-881-5; Vistogard; Uridine 2',3',5'-triacetate; 2',3',5'-Tri-O-acetyl-rU; 2',3',5'-Triacetyluridine; Uridine, 2',3',5'-triacetate; 2`,3`,5`-Tracetyluridine; TAU; 2',3',5'-Tri-O-acety; Tri-O-acetyl uridine; 2',3',5'-Tri0acetyluridine; 2',3',5'-Tri-O-acetyluridine; 2',3',5'-Triacetyluridine; O2',O3',O5'-triacetyl-uridine; uridine triacetate; Xuriden; 2',3',5'-O-triacetyluridine; 2`,3`,5`-Triacetyluridine; 2',3',5'-trioacetyluridine; MFCD00023795; Vistonuridine

Molecular FormulaC15H18N2O9

Molecular Weight370.319

Purity98%

Density1.4±0.1 g/cm3

Boiling Point

Melting Point124-134ºC

Flash Point

AppearanceWhite or almost white crystalline powder

EINECS223-881-5

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9001623 Purity: 98%
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Quality Control of [ 4105-38-8 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number4105-38-8
Catalog No.2A-9001623
Chinese Name2,3,5-三乙酰尿苷
Synonyms2',3',5-TRI-ACETYLURIDINE; EINECS 223-881-5; Vistogard; Uridine 2',3',5'-triacetate; 2',3',5'-Tri-O-acetyl-rU; 2',3',5'-Triacetyluridine; Uridine, 2',3',5'-triacetate; 2`,3`,5`-Tracetyluridine; TAU; 2',3',5'-Tri-O-acety; Tri-O-acetyl uridine; 2',3',5'-Tri0acetyluridine; 2',3',5'-Tri-O-acetyluridine; 2',3',5'-Triacetyluridine; O2',O3',O5'-triacetyl-uridine; uridine triacetate; Xuriden; 2',3',5'-O-triacetyluridine; 2`,3`,5`-Triacetyluridine; 2',3',5'-trioacetyluridine; MFCD00023795; Vistonuridine
Molecular FormulaC15H18N2O9
Molecular Weight370.319
Purity98
Density1.4±0.1 g/cm3
Melting Point124-134ºC
AppearanceWhite or almost white crystalline powder
Water SolubilitySoluble in: methanol
Storage Condition−20°C
ApplicationUridine triacetate (Tri-O-acetyl uridine) is an oral prodrug of uridine. Uridine triacetate (Tri-O-acetyl uridine) is highly fat-soluble, rapidly absorbed in the intestine, and rapidly deacetylated in
EINECS223-881-5
HTC2933.59.0500
MDL NumberMFCD07798677
SMILESCC(=O)OCC1OC(n2ccc(=O)[nH]c2=O)C(OC(C)=O)C1OC(C)=O
InChIInChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
InChI KeyAUFUWRKPQLGTGF-FMKGYKFTSA-N
Hazard SymbolsTransport
MSDSmsds/1623_1_4105_38_8.pdf
BioactivityUridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. Related Catalog Signaling Pathways >> Others >> Others References [1]. Ma WW, et al. Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Cancer. 2017 Jan 1;123(2):345-356. [2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Melting Point 124-134ºC Molecular Formula C15H18N2O9 Molecular Weight 370.311 Exact Mass 370.101227 PSA 142.99000 LogP -0.11 Index of Refraction 1.552 InChIKey AUFUWRKPQLGTGF-FMKGYKFTSA-N SMILES CC(=O)OCC1OC(n2ccc(=O)[nH]c2=O)C(OC(C)=O)C1OC(C)=O Storage condition −20°C
Use ofUridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. Properties Name 2',3',5'-Tri-O-acetyluridine Synonym More Synonyms uridine triacetate Biological Activity Description Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. Related Catalog Signaling Pathways >> Others >> Others References [1]. Ma WW, et al. Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Cancer. 2017 Jan 1;123(2):345-356. [2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8. Chemical & Physical Properties Molecular Formula C15H18N2O9 Exact Mass 370.101227 PSA 142.99000 LogP -0.11 Index of Refraction 1.552 InChIKey AUFUWRKPQLGTGF-FMKGYKFTSA-N
Transport InfoProduct name: Purity: 99.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available
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