CAS Number51-67-2
SynonymsUteramine; Tyramin; MFCD00008193; 4-Ethylaminophenol; Tocosine; 4-(2-aminoethyl)phenol; 4-(2-aminoethyl)-pheno; p-Hydroxyphenylethylamine; Tyrosamine; Systogene; 4-Hydroxyphenethylamine; p-Tyramine; 4-(Ethylamino)phenol; 4-(Ethylamino)benzolol; 2-(4-Hydroxyphenyl)ethylamine; EINECS 200-115-8; 4-hydroxy-phenethylamine
Molecular FormulaHOC6H4CH2CH2NH2
Molecular Weight137.18
Purity≥98.0%
Density1.1±0.1 g/cm3
Boiling Point175-181 °C/8 mmHg (lit.)
Melting Point160-162 °C (lit.)
Appearanceyellow to brown crystals
EINECS200-115-8
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51-67-2 |
| Catalog No. | 2A-9013527 |
| Chinese Name | 酪胺 |
| Synonyms | Uteramine; Tyramin; MFCD00008193; 4-Ethylaminophenol; Tocosine; 4-(2-aminoethyl)phenol; 4-(2-aminoethyl)-pheno; p-Hydroxyphenylethylamine; Tyrosamine; Systogene; 4-Hydroxyphenethylamine; p-Tyramine; 4-(Ethylamino)phenol; 4-(Ethylamino)benzolol; 2-(4-Hydroxyphenyl)ethylamine; EINECS 200-115-8; 4-hydroxy-phenethylamine |
| Molecular Formula | HOC6H4CH2CH2NH2 |
| Molecular Weight | 137.18 |
| Purity | ≥98.0 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 175-181 °C/8 mmHg (lit.) |
| Melting Point | 160-162 °C (lit.) |
| Appearance | yellow to brown crystals |
| Water Solubility | 1g/95mL (15 ºC) |
| Storage Condition | It should be sealed with argon gas and stored away |
| Application | Tyramine is an indirect acting sympathetic amine that releases norepinephrine from presynaptic nerve terminals. |
| EINECS | 200-115-8 |
| HTC | 2922299090 |
| PubChem ID | 24900582 |
| MDL Number | MFCD00008193 |
| SMILES | NCCc1ccc(O)cc1 |
| InChI | 1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2 |
| InChI Key | DZGWFCGJZKJUFP-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1099914 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/13527_1_51_67_2.pdf |
| Bioactivity | Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals. Related Catalog Research Areas >> Neurological Disease Natural Products >> Others Target Human Endogenous Metabolite In Vitro Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals[1]. Tyramine potentiates the postsynaptic inhibitory effects of norepinephrine on the firing of cortical neurones in the rat[2]. Although tyramine exists in three isomerie forms, the orthoisomer and metaisomers are present in very low concentrations and it is the paraisomer that is implied when reference is made to tyramine. The tyramines are generally present in nanogram/gram concentrations in brain tissue, but they have a very rapid turnover. The CNS role of tyramine is unclear, it has been suggested that it is involved in the modulation of dopamine synthesis and may also regulate norepinephrine turnover[3]. References [1]. Harrison WM, et al. The tyramine challenge test as a marker for melancholia. Arch Gen Psychiatry. 1984 Jul;41(7):681-5. [2]. BURN JH, et al. The action of sympathomimetic amines in animals treated with reserpine. J Physiol. 1958 Dec 4;144(2):314-36. [3]. Juorio AV, et al. A possible role for tyramines in brain function and some mental disorders. Gen Pharmacol. 1982;13(3):181-3. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 275.1±23.0 °C at 760 mmHg Melting Point 160-162 °C(lit.) Molecular Formula C8H11NO Molecular Weight 137.179 Flash Point 141.3±13.3 °C Exact Mass 137.084061 PSA 46.25000 LogP 1.38 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.600 InChIKey DZGWFCGJZKJUFP-UHFFFAOYSA-N SMILES NCCc1ccc(O)cc1 Storage condition Refrigerator, Under Inert Atmosphere Stability Stable. Incompatible with strong acids, strong oxidizing agents. Water Solubility 1g/95mL (15 ºC) |
| Use of | Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals. Properties Articles138 Name tyramine Synonym More Synonyms Tyramine Biological Activity Description Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals. Related Catalog Research Areas >> Neurological Disease Natural Products >> Others Human Endogenous Metabolite In Vitro Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals[1]. Tyramine potentiates the postsynaptic inhibitory effects of norepinephrine on the firing of cortical neurones in the rat[2]. Although tyramine exists in three isomerie forms, the orthoisomer and metaisomers are present in very low concentrations and it is the paraisomer that is implied when reference is made to tyramine. The tyramines are generally present in nanogram/gram concentrations in brain tissue, but they have a very rapid turnover. The CNS role of tyramine is unclear, it has been suggested that it is involved in the modulation of dopamine synthesis and may also regulate norepinephrine turnover[3]. References [1]. Harrison WM, et al. The tyramine challenge test as a marker for melancholia. Arch Gen Psychiatry. 1984 Jul;41(7):681-5. [2]. BURN JH, et al. The action of sympathomimetic amines in animals treated with reserpine. J Physiol. 1958 Dec 4;144(2):314-36. [3]. Juorio AV, et al. A possible role for tyramines in brain function and some mental disorders. Gen Pharmacol. 1982;13(3):181-3. Chemical & Physical Properties Molecular Formula C8H11NO Exact Mass 137.084061 PSA 46.25000 Index of Refraction 1.600 InChIKey DZGWFCGJZKJUFP-UHFFFAOYSA-N Storage condition Refrigerator, Under Inert Atmosphere Stability Stable. Incompatible with strong acids, strong oxidizing agents. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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