CAS Number99-96-7
Synonyms4-Hydroxybenzoicacid; Benzoic acid,4-hydroxy; PARAHYDROXY BENZOIC ACID; MFCD00002547; EINECS 202-804-9; 4-Hydroxybenzoic acid; p-Salicylic acid; 4-Hydroxy benzoic acid; HYDROXYBENZOIC ACID, P- POLYMER GRADE; |p|-Hydroxybenzoic acid; 4-Hydroxybenzoesaeure; Benzoic acid,p-hydroxy; P-HYDROXYBENZOIC ACID, REAGENT; PROPYL PARAHYDROXYBENZOATE IMP. A (EP): 4-HYDROXYBENZOIC ACID, CRM STANDARD; 1-Naphthyl phsophoric acid sodium salt; 4-Carboxyphenol; p-Hydroxybenzoic acid; para-Hydroxybenzoic acid; 4-hydroxy-benzoic acid; papa-hydroxy-benzoic acid; p-carboxyphenol
Molecular FormulaHOC6H4CO2H
Molecular Weight138.12
Purity≥99%
Density1.4±0.1 g/cm3
Boiling Point336.2±25.0 °C at 760 mmHg
Melting Point213-217 °C (lit.)
Appearancepowder
EINECS202-804-9
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 99-96-7 |
| Catalog No. | 2A-9013522 |
| Chinese Name | 4-羟基苯甲酸 |
| Synonyms | 4-Hydroxybenzoicacid; Benzoic acid,4-hydroxy; PARAHYDROXY BENZOIC ACID; MFCD00002547; EINECS 202-804-9; 4-Hydroxybenzoic acid; p-Salicylic acid; 4-Hydroxy benzoic acid; HYDROXYBENZOIC ACID, P- POLYMER GRADE; |p|-Hydroxybenzoic acid; 4-Hydroxybenzoesaeure; Benzoic acid,p-hydroxy; P-HYDROXYBENZOIC ACID, REAGENT; PROPYL PARAHYDROXYBENZOATE IMP. A (EP): 4-HYDROXYBENZOIC ACID, CRM STANDARD; 1-Naphthyl phsophoric acid sodium salt; 4-Carboxyphenol; p-Hydroxybenzoic acid; para-Hydroxybenzoic acid; 4-hydroxy-benzoic acid; papa-hydroxy-benzoic acid; p-carboxyphenol |
| Molecular Formula | HOC6H4CO2H |
| Molecular Weight | 138.12 |
| Purity | ≥99 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 336.2±25.0 °C at 760 mmHg |
| Melting Point | 213-217 °C (lit.) |
| Appearance | powder |
| Water Solubility | 5 g/L (20 ºC) |
| Storage Condition | 1. Store in a cool, ventilated warehouse. Keep awa |
| Application | 4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria. Its IC50 value is 160 μg/mL. |
| EINECS | 202-804-9 |
| HTC | 2916399090 |
| PubChem ID | 24854406 |
| MDL Number | MFCD00002547 |
| SMILES | OC(=O)c1ccc(O)cc1 |
| InChI | 1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) |
| InChI Key | FJKROLUGYXJWQN-UHFFFAOYSA-N |
| Beilstein/REAXYS | 970950 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Bioactivity | 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Phenylpropanoids Research Areas >> Infection Target Human Endogenous Metabolite Bacteria:160 μg/mL (IC50) In Vitro Most of the gram-positive and some gram-negative bacteria are sensitive to trans 4-Hydroxycinnamic acid (4-HBA) and 4-Hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 μg/mL, respectively. The antimicrobial activities of 4-Hydroxycinnamic acid and t4-HCA against 11 food pathogenic bacteria, 6 plant pathogenic bacteria, 2 yeasts and 15 plant pathogenic fungi are tested by the paper disc method. These compounds inhibit the growth of most of the bacteria and yeasts at concentrations of 200-400 μg. However, the inhibition is more effective against most of the gram-positive bacteria. When tested by the paper disc method, 4-Hydroxycinnamic acid has stronger antimicrobial activity than t4-HCA against S. aureus, L. mesenteroides, S. cerevisiae and C. albicans at a concentration of 50 μg. However, no inhibitory effect against fungi was observed at concentrations even up to 1000 μg[1]. References [1]. Cho JY, Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 336.2±25.0 °C at 760 mmHg Melting Point 213-217 °C(lit.) Molecular Formula C7H6O3 Molecular Weight 138.121 Flash Point 171.3±19.7 °C Exact Mass 138.031693 PSA 57.53000 LogP 1.42 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.616 InChIKey FJKROLUGYXJWQN-UHFFFAOYSA-N SMILES O=C(O)c1ccc(O)cc1 Storage condition Refrigerator Water Solubility 5 g/L (20 ºC) |
| Use of | 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. Properties Articles120 Name 4-hydroxybenzoic acid Synonym More Synonyms 4-Hydroxybenzoic acid Biological Activity Description 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Phenylpropanoids Research Areas >> Infection Human Endogenous Metabolite Bacteria:160 μg/mL (IC50) References [1]. Cho JY, Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6. Chemical & Physical Properties Molecular Formula C7H6O3 Exact Mass 138.031693 PSA 57.53000 Index of Refraction 1.616 InChIKey FJKROLUGYXJWQN-UHFFFAOYSA-N Storage condition Refrigerator |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Chemical name |
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