CAS Number623-05-2
Synonyms4-(Hydroxymethyl)benzolol; (4-Hydroxyphenyl)methanol; Gastrodigenin; p-Methylolphenol; 4-hydroxymethyl-phenol; PARA-ALCOHOLPHENOL; 4-Hydroxybenzyl alcohol; 4-hydroxybenzyl-alcohol; p-(Hydroxymethyl)phenol; p-Hydroxybenzyl; 4-(Hydroxymethyl)phenol; RARECHEM AL BD 0098; EINECS 210-768-0; 4-METHYLOLPHENOL; P-HYDROXYBENZYL ALCOHOL; MFCD00004658; 4-HYDROXY-BENZYL-ALCOHOL; α-Hydroxy-p-cresol; FEMA 3987
Molecular FormulaHOC6H4CH2OH
Molecular Weight124.14
Purity99%
Density1.2±0.1 g/cm3
Boiling Point252.0±0.0 °C at 760 mmHg
Melting Point114-122 °C (lit.)
Appearancepowder or crystals
EINECS210-768-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 623-05-2 |
| Catalog No. | 2A-9013523 |
| Chinese Name | 对羟基苯甲醇 |
| Synonyms | 4-(Hydroxymethyl)benzolol; (4-Hydroxyphenyl)methanol; Gastrodigenin; p-Methylolphenol; 4-hydroxymethyl-phenol; PARA-ALCOHOLPHENOL; 4-Hydroxybenzyl alcohol; 4-hydroxybenzyl-alcohol; p-(Hydroxymethyl)phenol; p-Hydroxybenzyl; 4-(Hydroxymethyl)phenol; RARECHEM AL BD 0098; EINECS 210-768-0; 4-METHYLOLPHENOL; P-HYDROXYBENZYL ALCOHOL; MFCD00004658; 4-HYDROXY-BENZYL-ALCOHOL; α-Hydroxy-p-cresol; FEMA 3987 |
| Molecular Formula | HOC6H4CH2OH |
| Molecular Weight | 124.14 |
| Purity | 99 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 252.0±0.0 °C at 760 mmHg |
| Melting Point | 114-122 °C (lit.) |
| Appearance | powder or crystals |
| Storage Condition | Store in a sealed container in a cool, dry place. |
| Application | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various plants. Has anti-inflammatory, antioxidant, and antinociceptive activities. Neuroprotective effects. Inhibit tumor angiogen |
| EINECS | 210-768-0 |
| HTC | 29072900 |
| PubChem ID | 24895499 |
| MDL Number | MFCD00004658 |
| SMILES | OCc1ccc(O)cc1 |
| InChI | 1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 |
| InChI Key | BVJSUAQZOZWCKN-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1858967 |
| NACRES Code | NA.22 |
| UNSPSC | 12164502 |
| Hazard Symbols | Transport |
| MSDS | msds/13523_1_623_05_2.pdf |
| Bioactivity | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Natural Products >> Phenols In Vitro 4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization[2]. 4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells[3]. In Vivo 4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production[1]. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors[3]. 4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway[4]. References [1]. Lim EJ, et al. Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol. J Pharm Pharmacol. 2007 Sep;59(9):1235-40. [2]. Laschke MW, et al. In vitro and in vivo evaluation of the anti-angiogenic actions of 4-hydroxybenzyl alcohol. Br J Pharmacol. 2011 Jun;163(4):835-44. [3]. Laschke MW, et al. 4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. Life Sci. 2013 Jul 19;93(1):44-50. [4]. Yu SS, et al. Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats. Brain Res. 2010 Jan 13;1308:167-75. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 252.0±0.0 °C at 760 mmHg Melting Point 114-122 °C(lit.) Molecular Formula C7H8O2 Molecular Weight 124.137 Flash Point 145.8±15.0 °C Exact Mass 124.052429 PSA 40.46000 LogP 0.30 Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.596 InChIKey BVJSUAQZOZWCKN-UHFFFAOYSA-N SMILES OCc1ccc(O)cc1 Storage condition 2-8°C |
| Use of | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. Properties Articles31 Name p-hydroxybenzyl alcohol Synonym More Synonyms 4-Hydroxybenzyl alcohol Biological Activity Description 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Natural Products >> Phenols References [1]. Lim EJ, et al. Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol. J Pharm Pharmacol. 2007 Sep;59(9):1235-40. [2]. Laschke MW, et al. In vitro and in vivo evaluation of the anti-angiogenic actions of 4-hydroxybenzyl alcohol. Br J Pharmacol. 2011 Jun;163(4):835-44. [3]. Laschke MW, et al. 4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. Life Sci. 2013 Jul 19;93(1):44-50. [4]. Yu SS, et al. Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats. Brain Res. 2010 Jan 13;1308:167-75. Chemical & Physical Properties Molecular Formula C7H8O2 Exact Mass 124.052429 PSA 40.46000 Index of Refraction 1.596 InChIKey BVJSUAQZOZWCKN-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 4-Hydrazinobenzoic acid hydrochloride | 24589-77-3 | 2A-9013517 |
| 4'-Hydroxy-3'-nitroacetophenone | 6322-56-1 | 2A-9013518 |
| 4-hydroxy-4-methyl-2-pentanone | 123-42-2 | 2A-9013520 |
| 4-Hydroxybenzenesulfonic acid | 98-67-9 | 2A-9013521 |
| 4-Hydroxybenzoic acid | 99-96-7 | 2A-9013522 |
| 4-Hydroxydiphenyl ether | 831-82-3 | 2A-9013525 |
| 4-Hydroxyphenethylamine | 51-67-2 | 2A-9013527 |
| 4-Hydroxyphenylacetic acid methyl ester | 14199-15-6 | 2A-9013528 |
| 4-Hydroxyphenylacetonitrile | 14191-95-8 | 2A-9013529 |
| 4'-Hydroxypropiophenone | 70-70-2 | 2A-9013530 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS