CAS Number58-85-5
SynonymsD(+)-Biotin; cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid; (+)-Biotin; EINECS 200-399-3; Bios-IIb; biotina; (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid; Rovimix H2; biotine; Rovimix H 2; Vitamin H; BIOS H; 5-[(3aR,6S,6aS)-2-Hydroxy-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid; biotin; Meribin; Ritatin; BIOTINUM; Lutavit H2; MFCD00005541; Factor S; biosii; Biodermatin; D-(+)-Biotin; D-Biotin; Vitamin B7
Molecular FormulaC10H16N2O3S
Molecular Weight244.31
Purity≥99 (HPLC)%
Density1.6±0.1 g/cm3
Boiling Point492.3±55.0 °C at 760 mmHg
Melting Point231-233 °C (lit.)
Appearancelyophilized powder
EINECS200-399-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 58-85-5 |
| Catalog No. | 2A-9012948 |
| Chinese Name | D-生物素 |
| Synonyms | D(+)-Biotin; cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid; (+)-Biotin; EINECS 200-399-3; Bios-IIb; biotina; (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid; Rovimix H2; biotine; Rovimix H 2; Vitamin H; BIOS H; 5-[(3aR,6S,6aS)-2-Hydroxy-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid; biotin; Meribin; Ritatin; BIOTINUM; Lutavit H2; MFCD00005541; Factor S; biosii; Biodermatin; D-(+)-Biotin; D-Biotin; Vitamin B7 |
| Molecular Formula | C10H16N2O3S |
| Molecular Weight | 244.31 |
| Purity | ≥99 (HPLC) |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 492.3±55.0 °C at 760 mmHg |
| Melting Point | 231-233 °C (lit.) |
| Appearance | lyophilized powder |
| Storage Condition | This product should be sealed, dry and protected f |
| Application | Biotin is water-soluble vitamin B7, a coenzyme of various carboxylase enzymes, and plays the role of CO2 carrier in carboxylase reactions. |
| EINECS | 200-399-3 |
| HTC | 29362930 |
| PubChem ID | 24891778 |
| MDL Number | MFCD00005541 |
| SMILES | [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 |
| InChI | 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 |
| InChI Key | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
| Beilstein/REAXYS | 86838 |
| NACRES Code | NA.21 |
| eCl@ss | 34058011 |
| UNSPSC | 12352201 |
| Hazard Symbols | Transport |
| MSDS | msds/12948_1_58_85_5.pdf |
| Bioactivity | Biotin is a water-soluble, enzyme co-factor present in minute amounts in every living cell.Target: OthersBiotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. The dietary biotin intake in Western populations has been estimated to be 35 to 70 microg/d (143-287 nmol/d). Recent studies suggest that humans absorb biotin nearly completely. Conditions that may increase biotin requirements in humans include pregnancy, lactation, and therapy with anticonvulsants or lipoic acid [1, 2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Others References [1]. Zempleni, J. and D.M. Mock, Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10(3): p. 128-38. [2]. Mock, D.M., Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129(2S Suppl): p. 498S-503S. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 492.3±55.0 °C at 760 mmHg Melting Point 231-233 °C(lit.) Molecular Formula C10H16N2O3S Molecular Weight 244.311 Flash Point 251.5±31.5 °C Exact Mass 244.088165 PSA 103.73000 LogP 0.03 Vapour Pressure 0.0±2.8 mmHg at 25°C Index of Refraction 1.717 InChIKey YBJHBAHKTGYVGT-ZKWXMUAHSA-N SMILES O=C(O)CCCCC1SCC2NC(=O)NC21 |
| Use of | Properties Articles148 Name biotin Synonym More Synonyms D-Biotin Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Others References [1]. Zempleni, J. and D.M. Mock, Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10(3): p. 128-38. [2]. Mock, D.M., Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129(2S Suppl): p. 498S-503S. Chemical & Physical Properties Molecular Formula C10H16N2O3S Exact Mass 244.088165 PSA 103.73000 Index of Refraction 1.717 InChIKey YBJHBAHKTGYVGT-ZKWXMUAHSA-N SMILES O=C(O)CCCCC1SCC2NC(=O)NC21 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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