CAS Number122946-43-4
Synonyms(R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid; Telmesteinum; Telmesteine (INN); Telmesteine; Telmesteina; (R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester; Reolase (TN); N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid; (R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester; Telmesteinum [INN-Latin]; UNII-124I3FE35T
Molecular FormulaC7H11O4N1S1
Molecular Weight205.23
Purity98.00%
Density1.409g/cm3
Boiling Point386.221ºC at 760 mmHg
Melting Point98ºC
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 122946-43-4 |
| Catalog No. | 2A-9012610 |
| Chinese Name | 替美司坦 |
| Synonyms | (R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid; Telmesteinum; Telmesteine (INN); Telmesteine; Telmesteina; (R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester; Reolase (TN); N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid; (R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester; Telmesteinum [INN-Latin]; UNII-124I3FE35T |
| Molecular Formula | C7H11O4N1S1 |
| Molecular Weight | 205.23 |
| Purity | 98.00 |
| Density | 1.409g/cm3 |
| Boiling Point | 386.221ºC at 760 mmHg |
| Melting Point | 98ºC |
| Application | Telmesteine is an anti-adhesive agent. Telmesteine has antiprotease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used to study inflammation, s |
| HTC | 2934999090 |
| MDL Number | MFCD04117921 |
| SMILES | CCOC(=O)N1CSCC1C(=O)O |
| InChI | InChI=1S/C7H11NO4S/c1-2-12-7(11)8-4-13-3-5(8)6(9)10/h5H,2-4H2,1H3,(H,9,10)/t5-/m0/s1 |
| InChI Key | XBJWOGLKABXFJE-YFKPBYRVSA-N |
| MSDS | msds/12610_1_122946_43_4.pdf |
| Use of | Properties Name (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid Synonym More Synonyms Telmesteine Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65. [2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704. Chemical & Physical Properties Molecular Formula C7H11NO4S Exact Mass 205.04100 PSA 92.14000 LogP 0.54030 Index of Refraction 1.562 InChIKey XBJWOGLKABXFJE-YFKPBYRVSA-N Safety Information HS Code 2934999090 Synthetic Route Total: 1 Page Ethyl chloroformate CAS#:541-41-3 L-Thioproline CAS#:34592-47-7 Telmesteine CAS#:122946-43-4 Literature: Braibante, Mara E.F.; Braibante, Hugo S.; Costenaro, Edson R. Synthesis, 1999 , # 6 p. 943 - 946 Ethyl chloroformate CAS#:541-41-3 Telmesteine CAS#:122946-43-4 Literature: Strukow Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 521,523; engl. Ausg. S. 587, 589 Precursor & DownStream Precursor 2 CAS#:541-41-3 Ethyl chloroformate CAS#:34592-47-7 L-Thioproline DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Tefenperate | 77342-26-8 | 2A-9012605 |
| Tefluthrin | 79538-32-2 | 2A-9012606 |
| Tegafur | 17902-23-7 | 2A-9012607 |
| Tegaserod maleate | 189188-57-6 | 2A-9012608 |
| Telimomabaritox | 117305-33-6 | 2A-9012609 |
| Teludipine | 108687-08-7 | 2A-9012612 |
| Temafloxacin | 108319-06-8 | 2A-9012613 |
| Temarotene | 75078-91-0 | 2A-9012614 |
| Temeguard | 3383-96-8 | 2A-9012615 |
| Temocapril | 111902-57-9 | 2A-9012616 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS