Rimantadine structure, CAS 13392-28-4

Rimantadine

CAS Number13392-28-4

Synonyms1-adamantanemethylamine; tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride; a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride; Remantadine; Meradan; α-Methyl-1-adamantanemethylamine hydrochloride; UNII:JEI07OOS8Y; [1-(1-Adamantyl)ethyl]amine hydrochloride; Rimant; MFCD03265511; 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate; 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1); Roflual; Rimantadinum; 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1); Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1); Flumadine; a-Methyl-1-adamantanemethylamine Hydrochloride; 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid; Rimantadina; Rimantadine; Rimantadine Hydrochloride; 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride; Riamantadine; Remantad

Molecular FormulaC12H21N

Molecular Weight179.31

Purity98%

Density1.033

Boiling Point248ºC

Melting Point375°C(lit.)

Flash Point

AppearanceWhite-off-white crystal-powder

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9012308 Purity: 98%
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Quality Control of [ 13392-28-4 ] Purity: 98% SDS Specification MoL

Chemical & Physical Properties
CAS Number13392-28-4
Catalog No.2A-9012308
Chinese Name1-金刚烷乙胺
Synonyms1-adamantanemethylamine; tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride; a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride; Remantadine; Meradan; α-Methyl-1-adamantanemethylamine hydrochloride; UNII:JEI07OOS8Y; [1-(1-Adamantyl)ethyl]amine hydrochloride; Rimant; MFCD03265511; 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate; 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1); Roflual; Rimantadinum; 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1); Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1); Flumadine; a-Methyl-1-adamantanemethylamine Hydrochloride; 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid; Rimantadina; Rimantadine; Rimantadine Hydrochloride; 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride; Riamantadine; Remantad
Molecular FormulaC12H21N
Molecular Weight179.31
Purity98
Density1.033
Boiling Point248ºC
Melting Point375°C(lit.)
AppearanceWhite-off-white crystal-powder
Storage Condition-20°C
ApplicationRimantadine (Flumadine) is an anti-influenza virus compound.
HTC2921300090
MDL NumberC12H21N
SMILESCC(N)C12CC3CC(CC(C3)C1)C2
InChIInChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3
InChI KeyUBCHPRBFMUDMNC-UHFFFAOYSA-N
Hazard SymbolsTransport
MSDSmsds/12308_1_13392_28_4.pdf
BioactivityRimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82. Chemical & Physical Properties Density 1.033 Boiling Point 248ºC Melting Point 375°C(lit.) Molecular Formula C12H21N Molecular Weight 179.30 Flash Point 99ºC PSA 26.02000 LogP 4.05230 Vapour Pressure 0.0249mmHg at 25°C Index of Refraction 1.539 InChIKey UBCHPRBFMUDMNC-UHFFFAOYSA-N SMILES CC(N)C12CC3CC(CC(C3)C1)C2 Storage condition -20°C
Use ofProperties Name 1-(1-adamantyl)ethanamine Synonym More Synonyms Rimantadine Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82. Chemical & Physical Properties Molecular Formula C12H21N PSA 26.02000 LogP 4.05230 Index of Refraction 1.539 InChIKey UBCHPRBFMUDMNC-UHFFFAOYSA-N
Tax Rebate9.0%
SupervisionNone MFN tariff: 6.5% Ordinary tariff: 30.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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