
CAS Number13392-28-4
Synonyms1-adamantanemethylamine; tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride; a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride; Remantadine; Meradan; α-Methyl-1-adamantanemethylamine hydrochloride; UNII:JEI07OOS8Y; [1-(1-Adamantyl)ethyl]amine hydrochloride; Rimant; MFCD03265511; 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate; 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1); Roflual; Rimantadinum; 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1); Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1); Flumadine; a-Methyl-1-adamantanemethylamine Hydrochloride; 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid; Rimantadina; Rimantadine; Rimantadine Hydrochloride; 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride; Riamantadine; Remantad
Molecular FormulaC12H21N
Molecular Weight179.31
Purity98%
Density1.033
Boiling Point248ºC
Melting Point375°C(lit.)
AppearanceWhite-off-white crystal-powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13392-28-4 |
| Catalog No. | 2A-9012308 |
| Chinese Name | 1-金刚烷乙胺 |
| Synonyms | 1-adamantanemethylamine; tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride; a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride; Remantadine; Meradan; α-Methyl-1-adamantanemethylamine hydrochloride; UNII:JEI07OOS8Y; [1-(1-Adamantyl)ethyl]amine hydrochloride; Rimant; MFCD03265511; 1-tricyclo[3.3.1.1]déc-1-yléthanamine chlorhydrate; 1-(Adamantan-1-yl)ethanamine hydrochloride (1:1); Roflual; Rimantadinum; 1-(tricyclo[3.3.1.1]dec-1-yl)ethanamine hydrochloride (1:1); Tricyclo[3.3.1.1]decane-1-methanamine, α-methyl-, hydrochloride (1:1); Flumadine; a-Methyl-1-adamantanemethylamine Hydrochloride; 1-Tricyclo[3.3.1.1]dec-1-ylethanaminhydrochlorid; Rimantadina; Rimantadine; Rimantadine Hydrochloride; 1-tricyclo[3.3.1.1]dec-1-ylethanamine hydrochloride; Riamantadine; Remantad |
| Molecular Formula | C12H21N |
| Molecular Weight | 179.31 |
| Purity | 98 |
| Density | 1.033 |
| Boiling Point | 248ºC |
| Melting Point | 375°C(lit.) |
| Appearance | White-off-white crystal-powder |
| Storage Condition | -20°C |
| Application | Rimantadine (Flumadine) is an anti-influenza virus compound. |
| HTC | 2921300090 |
| MDL Number | C12H21N |
| SMILES | CC(N)C12CC3CC(CC(C3)C1)C2 |
| InChI | InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3 |
| InChI Key | UBCHPRBFMUDMNC-UHFFFAOYSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/12308_1_13392_28_4.pdf |
| Bioactivity | Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82. Chemical & Physical Properties Density 1.033 Boiling Point 248ºC Melting Point 375°C(lit.) Molecular Formula C12H21N Molecular Weight 179.30 Flash Point 99ºC PSA 26.02000 LogP 4.05230 Vapour Pressure 0.0249mmHg at 25°C Index of Refraction 1.539 InChIKey UBCHPRBFMUDMNC-UHFFFAOYSA-N SMILES CC(N)C12CC3CC(CC(C3)C1)C2 Storage condition -20°C |
| Use of | Properties Name 1-(1-adamantyl)ethanamine Synonym More Synonyms Rimantadine Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82. Chemical & Physical Properties Molecular Formula C12H21N PSA 26.02000 LogP 4.05230 Index of Refraction 1.539 InChIKey UBCHPRBFMUDMNC-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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