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Pitavastatin calcium structure, CAS 147526-32-7

Pitavastatin calcium

CAS Number147526-32-7

SynonymsPitavastatin Calcium; Livalo; Calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}; MFCD01937979; UNII-IYD54XEG3W; Pitavastatin (Calcium); calcium,(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate; Livazo; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid; NK-104; [3H]-Pitavastatin; Alipza; Pitavastatin hemicalcium; Nisvastatin

Molecular FormulaC50H46O8N2F2Ca1

Molecular Weight881

Purity98%

Density

Boiling Point692ºC at 760 mmHg

Melting Point

Flash Point

AppearanceWhite to off-white powder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9012056 Purity: 98%
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Quality Control of [ 147526-32-7 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number147526-32-7
Catalog No.2A-9012056
Chinese Name匹伐他汀钙
SynonymsPitavastatin Calcium; Livalo; Calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}; MFCD01937979; UNII-IYD54XEG3W; Pitavastatin (Calcium); calcium,(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate; Livazo; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid; NK-104; [3H]-Pitavastatin; Alipza; Pitavastatin hemicalcium; Nisvastatin
Molecular FormulaC50H46O8N2F2Ca1
Molecular Weight881
Purity98
Boiling Point692ºC at 760 mmHg
AppearanceWhite to off-white powder
Storage Condition-20°C
ApplicationPitavastatin Calcium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase. Pitavastatin Calcium inhibits cholesterol synthesis from acetate in HepG2 cells with an IC50 of 5.8 nM.
HTC2933499090
MDL NumberMFCD00916490
SMILESO=C(O)CC(O)CC(O)C=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.[Ca]
InChIInChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
InChI KeyAMUDYCAFPCQTAZ-NRFPMOEYSA-N
MSDSmsds/12056_1_147526_32_7.pdf
Use ofProperties Name pitavastatin calcium Synonym More Synonyms Pitavastatin calcium Biological Activity Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Signaling Pathways >> Autophagy >> Mitophagy Research Areas >> Metabolic Disease References [1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52. [2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215. Chemical & Physical Properties PSA 186.96000 LogP 6.36680 InChIKey AMUDYCAFPCQTAZ-NRFPMOEYSA-N Safety Information Hazard Codes Xi HS Code 2933499090 Synthetic Route Pitavastatin ca... 147526-32-7 Pitavastatin ca... 147526-32-7 Tert-buthyl Pit... 586966-54-3 Pitavastatin ca... 147526-32-7 Ethyl (E)-7-[4-... 148901-69-3 Pitavastatin ca... 147526-32-7 Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 20 p. 2977 - 2982 Precursor & DownStream Precursor 10 CAS#:147526-32-7 Pitavastatin calcium CAS#:586966-54-3 Tert-buthyl Pit... CAS#:148901-69-3 Ethyl (E)-7-[4-... CAS#:166803-31-2 (E)-7-[2-cyclop... DownStream 1 CAS#:147526-32-7 Pitavastatin calcium
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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