CAS Number78712-43-3
Synonyms(2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid hydrochloride hydrate; Ozagrel hydrochloride; 2-Propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, (2E)-, hydrochloride, hydrate (1:1:1); MFCD06795644
Molecular FormulaC13H15ClN2O3
Molecular Weight264.71 (anhydrous basis)
Purity≥98 (HPLC)%
Boiling Point468ºC at 760 mmHg
Melting Point217 °C
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 78712-43-3 |
| Catalog No. | 2A-9011847 |
| Chinese Name | 盐酸奥扎格雷 |
| Synonyms | (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid hydrochloride hydrate; Ozagrel hydrochloride; 2-Propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, (2E)-, hydrochloride, hydrate (1:1:1); MFCD06795644 |
| Molecular Formula | C13H15ClN2O3 |
| Molecular Weight | 264.71 (anhydrous basis) |
| Purity | ≥98 (HPLC) |
| Boiling Point | 468ºC at 760 mmHg |
| Melting Point | 217 °C |
| Appearance | solid |
| Water Solubility | H2O: soluble |
| Storage Condition | Room Temperature |
| Application | Ozagrel hydrochloride (OKY-046 hydrochloride) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel hydrochloride is an antiplatelet agent that selectively inhibits human platelet aggregation with an |
| HTC | 2942000000 |
| PubChem ID | 24897942 |
| MDL Number | MFCD00911569 |
| SMILES | O.Cl.OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 |
| InChI | 1S/C13H12N2O2.ClH.H2O/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;;/h1-8,10H,9H2,(H,16,17);1H;1H2/b6-5+;; |
| InChI Key | OWIZTYOMGVTSDP-TXOOBNKBSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/11847_1_78712_43_3.pdf |
| Bioactivity | Ozagrel hydrochloride (OKY-046 hydrochloride) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel hydrochloride is an antiplatelet agent, which selectively inhibits human platelet aggregationwith an IC50 of 53.12 μM[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Target TXA2 References [1]. Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601. Chemical & Physical Properties Boiling Point 468ºC at 760 mmHg Melting Point 217 °C Molecular Formula C13H15ClN2O3 Molecular Weight 282.723 Flash Point 236.8ºC Exact Mass 282.077118 PSA 64.35000 LogP 2.76690 InChIKey CWKFWBJJNNPGAM-IPZCTEOASA-N SMILES Cl.O=C(O)C=Cc1ccc(Cn2ccnc2)cc1 Water Solubility H2O: soluble |
| Use of | Ozagrel hydrochloride (OKY-046 hydrochloride) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel hydrochloride is an antiplatelet agent, which selectively inhibits human platelet aggregationwith an IC50 of 53.12 μM[1]. Properties Articles30 Name Ozagrel Hydrochloride Hydrate Synonym More Synonyms Ozagrel hydrochloride Biological Activity Description Ozagrel hydrochloride (OKY-046 hydrochloride) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel hydrochloride is an antiplatelet agent, which selectively inhibits human platelet aggregationwith an IC50 of 53.12 μM[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor References [1]. Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601. Chemical & Physical Properties Exact Mass 282.077118 PSA 64.35000 LogP 2.76690 InChIKey CWKFWBJJNNPGAM-IPZCTEOASA-N Water Solubility H2O: soluble |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Oxymetazoline | 1491-59-4 | 2A-9011839 |
| Oxymorphone | 76-41-5 | 2A-9011840 |
| Oxyphencyclimine | 125-52-0 | 2A-9011841 |
| Oxyridazine | 14759-04-7 | 2A-9011842 |
| Ozagrel | 82571-53-7 | 2A-9011846 |
| Ozagrel sodium | 130952-46-4 | 2A-9011848 |
| Pachycarpine | 492-08-0 | 2A-9011849 |
| Pacrinolol | 65655-59-6 | 2A-9011851 |
| Paeonol | 552-41-0 | 2A-9011852 |
| Pafenolol | 75949-61-0 | 2A-9011853 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS