| Chemical & Physical Properties | |
|---|---|
| CAS Number | 36531-26-7 |
| Catalog No. | 2A-9011809 |
| Chinese Name | 奥克生太 |
| Synonyms | UNII-94AJJ30D9E; OXANTEL; Oxantelum |
| Molecular Formula | C13H16N2O |
| Molecular Weight | 604.66 |
| Purity | 98 |
| Density | 1.09g/cm3 |
| Boiling Point | 383.1ºC at 760mmHg |
| Application | Oxantel (CP-14445) is a derivative of Pyrantel (HY-12641) and is an N-subtype AChR agonist. Oxantel is an insect repellent with excellent anthelmintic activity. |
| HTC | 2933599090 |
| MDL Number | C36H32N2O7 |
| SMILES | CN1CCCN=C1C=Cc1cccc(O)c1 |
| InChI | InChI=1S/C13H16N2O/c1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h2,4-7,10,16H,3,8-9H2,1H3/b7-6+ |
| InChI Key | VRYKTHBAWRESFI-VOTSOKGWSA-N |
| MSDS | msds/11809_1_36531_26_7.pdf |
| Use of | Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties[1][2]. Properties Name 3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol Synonym More Synonyms Oxantel Biological Activity Description Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR nAChR[1][2] In Vitro Oxantel ( 0.015-600 µg/mL; 24-72 hours) reduces the viability of T. muris[1]. Cell Viability Assay Cell Line: T. muris Concentration: 0.015 µg/mL, 0.3 µg/mL, 0.6 µg/mL, 4.66 µg/mL, 9.375 µg/mL, 150 µg/mL, 600 µg/mL Incubation Time: 24 hours, 48 hours, 72 hours Result: Resulted in strongly reduced viabilities; resulted in strongly reduced viabilities within 24 hours but did not kill the worms. References [1]. Richard J Martin, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug;34(9):1083-90. [2]. V M Dale, et al. Oxantel-activated single channel currents in the muscle membrane of Ascaris suum. Parasitology. 1995 May;110 ( Pt 4):437-48. Chemical & Physical Properties Molecular Formula C13H16N2O Exact Mass 216.12600 PSA 35.83000 LogP 1.51290 Index of Refraction 1.575 InChIKey VRYKTHBAWRESFI-VOTSOKGWSA-N Safety Information HS Code 2933599090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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