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Ornidazole structure, CAS 16773-42-5

Ornidazole

CAS Number16773-42-5

Synonyms1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole; α-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol; α-(Chloromethyl)-2-methyl-5-nitroimidazole-1-ethanol; UNII:62XCK0G93T; Ornidazole; 1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol; MFCD00057960; 1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)-2-propanol; a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol; 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol; EINECS 240-826-0

Molecular FormulaC7H10N3O3Cl

Molecular Weight219.63

Purity98%

Density1.5±0.1 g/cm3

Boiling Point443.2±40.0 °C at 760 mmHg

Melting Point85-90°C

Flash Point

Appearancecrystalline solid

EINECS240-826-0

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Cat. No.: 2A-9011790 Purity: 98%
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Quality Control of [ 16773-42-5 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number16773-42-5
Catalog No.2A-9011790
Chinese Name奥硝唑
Synonyms1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole; α-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol; α-(Chloromethyl)-2-methyl-5-nitroimidazole-1-ethanol; UNII:62XCK0G93T; Ornidazole; 1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol; MFCD00057960; 1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)-2-propanol; a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol; 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol; EINECS 240-826-0
Molecular FormulaC7H10N3O3Cl
Molecular Weight219.63
Purity98
Density1.5±0.1 g/cm3
Boiling Point443.2±40.0 °C at 760 mmHg
Melting Point85-90°C
Appearancecrystalline solid
Storage Condition-20°C Freezer
ApplicationOrnidazole (Ro 7-0207) is a 5-nitroimidazole derivative that can fight protozoa and anaerobic bacteria.
EINECS240-826-0
HTC2933290090
PubChem ID329818917
MDL NumberMFCD00057960
SMILESCc1ncc(n1CC(O)CCl)[N+]([O-])=O
InChI1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3
InChI KeyIPWKIXLWTCNBKN-UHFFFAOYSA-N
NACRES CodeNA.24
UNSPSC41116107
MSDSmsds/11790_1_16773_42_5.pdf
BioactivityOrnidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Target: Antibacterial; AntiparasiticOrnidazole is a drug that cures some protozoan infections. Ornidazole 1 g/day is effective for the prevention of recurrence of Crohn's disease after ileocolonic resection [1]. Ornidazole is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms [2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Natural Products >> Others References [1]. Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61. [2]. Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 443.2±40.0 °C at 760 mmHg Melting Point 85-90°C Molecular Formula C7H10ClN3O3 Molecular Weight 219.626 Flash Point 221.9±27.3 °C Exact Mass 219.041061 PSA 83.87000 LogP 0.69 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.617 InChIKey IPWKIXLWTCNBKN-UHFFFAOYSA-N SMILES Cc1ncc([N+](=O)[O-])n1CC(O)CCl Storage condition -20°C Freezer
Use ofProperties Articles32 Name ornidazole Synonym More Synonyms Ornidazole Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Natural Products >> Others References [1]. Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61. [2]. Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13. Chemical & Physical Properties Exact Mass 219.041061 PSA 83.87000 Index of Refraction 1.617 InChIKey IPWKIXLWTCNBKN-UHFFFAOYSA-N
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
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