CAS Number1063-77-0
Synonymsfromcitrusseeds; 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
Molecular FormulaC28H34O9
Molecular Weight514.56
Purity≥95.0 (HPLC)%
Density1.3±0.1 g/cm3
Boiling Point657.7±55.0 °C at 760 mmHg
Melting Point278-279°
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1063-77-0 |
| Catalog No. | 2A-9011696 |
| Chinese Name | 诺米林 |
| Synonyms | fromcitrusseeds; 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone |
| Molecular Formula | C28H34O9 |
| Molecular Weight | 514.56 |
| Purity | ≥95.0 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 657.7±55.0 °C at 760 mmHg |
| Melting Point | 278-279° |
| Appearance | solid |
| Storage Condition | Keep container sealed and stored in a cool, dry pl |
| Application | Nomilin is a limonoid compound obtained from citrus extracts. Nomilin is an anti-obesity and hypoglycemic agent. |
| MDL Number | MFCD00075979 |
| SMILES | CC(=O)OC1CC(=O)OC(C)(C)[C@@H]2CC(=O)[C@]3(C)[C@H](CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@@]345)c6ccoc6)[C@@]12C |
| InChI | 1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16-,17+,19?,21+,22-,25+,26-,27+,28-/m1/s1 |
| InChI Key | KPDOJFFZKAUIOE-BIYZDVJRSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11696_1_1063_77_0.pdf |
| Bioactivity | Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease In Vitro Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown[1]. In Vivo Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5[1]. References [1]. Shi YS, et al. Nomilin protects against cerebral ischemia-reperfusion induced neurological deficits and blood-brain barrier disruption via the Nrf2 pathway. Food Funct. 2019 Sep 1;10(9):5323-5332. [2]. Sato R, et al. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 657.7±55.0 °C at 760 mmHg Melting Point 278-279° Molecular Formula C28H34O9 Molecular Weight 514.564 Flash Point 351.6±31.5 °C Exact Mass 514.220276 PSA 121.64000 LogP 2.47 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.575 InChIKey KPDOJFFZKAUIOE-BIYZDVJRSA-N SMILES CC(=O)OC1CC(=O)OC(C)(C)C2CC(=O)C3(C)C(CCC4(C)C(c5ccoc5)OC(=O)C5OC543)C12C |
| Use of | Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. Properties Name Nomilin Synonym More Synonyms Biological Activity Description Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease In Vitro Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown[1]. In Vivo Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5[1]. References [1]. Shi YS, et al. Nomilin protects against cerebral ischemia-reperfusion induced neurological deficits and blood-brain barrier disruption via the Nrf2 pathway. Food Funct. 2019 Sep 1;10(9):5323-5332. [2]. Sato R, et al. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. Chemical & Physical Properties Molecular Formula C28H34O9 Exact Mass 514.220276 PSA 121.64000 Index of Refraction 1.575 InChIKey KPDOJFFZKAUIOE-BIYZDVJRSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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