
CAS Number10331-57-4
SynonymsBayer 9015; EINECS 233-720-0; ME 3625; Bilevon M; 5,5'-dichloro-3,3'-dinitro-2,2'-biphenyldiol; 5,5'-dichloro-3,3'-dinitrobiphenyl-2,2'-diol; Niclofolanum [INN-Latin]; Niclofolano [INN-Spanish]; 5,5'-Dichloro-3,3'-dinitro-[1,1'-biphenyl]-2,2'-diol; Niclofolan; BAY 9015; Menichlopholan; 2,2'-Dihydroxy-3,3'-dinitro-5,5'-dichlor-diphenyl
Molecular FormulaC12H6Cl2N2O6
Molecular Weight345.092
Purity98%
Density1.7±0.1 g/cm3
Boiling Point424.9±45.0 °C at 760 mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 10331-57-4 |
| Catalog No. | 2A-9011634 |
| Chinese Name | 硝氯酚 |
| Synonyms | Bayer 9015; EINECS 233-720-0; ME 3625; Bilevon M; 5,5'-dichloro-3,3'-dinitro-2,2'-biphenyldiol; 5,5'-dichloro-3,3'-dinitrobiphenyl-2,2'-diol; Niclofolanum [INN-Latin]; Niclofolano [INN-Spanish]; 5,5'-Dichloro-3,3'-dinitro-[1,1'-biphenyl]-2,2'-diol; Niclofolan; BAY 9015; Menichlopholan; 2,2'-Dihydroxy-3,3'-dinitro-5,5'-dichlor-diphenyl |
| Molecular Formula | C12H6Cl2N2O6 |
| Molecular Weight | 345.092 |
| Purity | 98 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 424.9±45.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | 2-8°C, protected from light, inert gas |
| Application | Nicotine (BAY 9015) is an orally active anthelmintic. Nicotine can be used in the study of parasitic infections [1][2][3]. |
| HTC | 2907299090 |
| SMILES | O=[N+]([O-])c1cc(Cl)cc(-c2cc(Cl)cc([N+](=O)[O-])c2O)c1O |
| InChI | InChI=1S/C12H6Cl2N2O6/c13-5-1-7(11(17)9(3-5)15(19)20)8-2-6(14)4-10(12(8)18)16(21)22/h1-4,17-18H |
| InChI Key | XULACPAEUUWKFX-UHFFFAOYSA-N |
| Use of | Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection[1][2][3]. Properties Name 4-chloro-2-(5-chloro-2-hydroxy-3-nitrophenyl)-6-nitrophenol Synonym More Synonyms Niclofolan Biological Activity Description Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection[1][2][3]. Related Catalog Research Areas >> Infection References [1]. T Eckhardt, Treatment of human fascioliasis with niclofolan. Gastroenterology. 1981 Oct; 81(4):795-8. [2]. B H Ali, T Hassan, et al. The effect of niclofolan on desert sheep experimentally infected with immature Fasciola gigantica. J Vet Pharmacol Ther. 1985 Dec;8(4):398-403. [3]. Santamarina M. T., et al. Anthelmintic treatment against Gyrodactylus sp. infecting rainbow trout Oncorhynchus mykiss. Diseases of Aquatic Organisms, 1991 10(1): 39-43. [4]. Rim H J, et al. Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis. The Korean Journal of Parasitology, 1976, 14(2): 140-146. Chemical & Physical Properties Exact Mass 343.960297 PSA 132.10000 Index of Refraction 1.706 InChIKey XULACPAEUUWKFX-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : (1,1'-Biphenyl)-2,2'-diol, 5,5'-dichloro-3,3'-dinitro- CAS REGISTRY NUMBER : 10331-57-4 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C12-H6-Cl2-N2-O6 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : WNR DQ CG ER BQ CG ENW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,525,1971 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Bird - wild bird species DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,525,1971 Safety Information Hazard Codes C HS Code 2907299090 |
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