CAS Number165800-03-3
SynonymsLinezolid; NDA 21-130 Zyvox; N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Linezlid; Zyvoxid; Zyvox; (S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide; N-{[(5S)-3-(3-Fluor-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamid; N-({(5S)-3-[3-Fluor-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamid; Zyvoxam; N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide; Zyvoxa; MFCD00937825; N-({(5S)-3-[3-Fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide; N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide; N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphényl)-2-oxo-1,3-oxazolidin-5-yl]méthyl}acétamide; N-({(5S)-3-[3-Fl
Molecular FormulaC16H20FN3O4
Molecular Weight337.35
Purity99%
Density1.3±0.1 g/cm3
Boiling Point585.5±50.0 °C at 760 mmHg
Melting Point176-1780C
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 165800-03-3 |
| Catalog No. | 2A-9011192 |
| Chinese Name | 利奈唑胺 |
| Synonyms | Linezolid; NDA 21-130 Zyvox; N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Linezlid; Zyvoxid; Zyvox; (S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide; N-{[(5S)-3-(3-Fluor-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamid; N-({(5S)-3-[3-Fluor-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamid; Zyvoxam; N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide; Zyvoxa; MFCD00937825; N-({(5S)-3-[3-Fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide; N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide; N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphényl)-2-oxo-1,3-oxazolidin-5-yl]méthyl}acétamide; N-({(5S)-3-[3-Fl |
| Molecular Formula | C16H20FN3O4 |
| Molecular Weight | 337.35 |
| Purity | 99 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 585.5±50.0 °C at 760 mmHg |
| Melting Point | 176-1780C |
| Appearance | powder |
| Water Solubility | Water solubility: insoluble; water solubility: 610 |
| Storage Condition | Store at RT |
| Application | Linezolid (PNU-100766) is a synthetic antibiotic used to treat serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. |
| HTC | 2934999090 |
| MDL Number | MFCD00937825 |
| SMILES | CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2 |
| InChI | 1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 |
| InChI Key | TYZROVQLWOKYKF-ZDUSSCGKSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11192_1_165800_03_3.pdf |
| Bioactivity | Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Clemett D, Markham A. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828. [2]. Chiappini E, Conti C, Galli L et al. Clinical efficacy and tolerability of linezolid in pediatric patients: a systematic review. Clin Ther. 2010 Jan;32(1):66-88. [3]. Perry CM, Jarvis B. Linezolid: a review of its use in the management of serious gram-positive infections. Drugs. 2001;61(4):525-51. [4]. He MZ, Jiang YW, Cai C.Mechanisms and epidemiology of linezolid resistance in staphylococci.Zhonghua Jie He He Hu Xi Za Zhi. 2012 May;35(5):360-2. [5]. Karau MJ, Tilahun AY, Schmidt SM, Clark CR, Patel R, Rajagopalan G.Linezolid is Superior to Vancomycin in Experimental Pneumonia Caused by Superantigen-Producing Staphylococcus aureus in HLA class II Transgenic Mice.Antimicrob Agents Chemother. 2012 Jul 30. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 585.5±50.0 °C at 760 mmHg Melting Point 176-1780C Molecular Formula C16H20FN3O4 Molecular Weight 337.346 Flash Point 307.9±30.1 °C Exact Mass 337.143799 PSA 71.11000 LogP 0.30 Vapour Pressure 0.0±1.6 mmHg at 25°C Index of Refraction 1.554 InChIKey TYZROVQLWOKYKF-ZDUSSCGKSA-N SMILES CC(=O)NCC1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1 Storage condition Store at RT |
| Use of | Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. Properties Articles73 Name linezolid Synonym More Synonyms Linezolid Biological Activity Description Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Clemett D, Markham A. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828. [2]. Chiappini E, Conti C, Galli L et al. Clinical efficacy and tolerability of linezolid in pediatric patients: a systematic review. Clin Ther. 2010 Jan;32(1):66-88. [3]. Perry CM, Jarvis B. Linezolid: a review of its use in the management of serious gram-positive infections. Drugs. 2001;61(4):525-51. [4]. He MZ, Jiang YW, Cai C.Mechanisms and epidemiology of linezolid resistance in staphylococci.Zhonghua Jie He He Hu Xi Za Zhi. 2012 May;35(5):360-2. [5]. Karau MJ, Tilahun AY, Schmidt SM, Clark CR, Patel R, Rajagopalan G.Linezolid is Superior to Vancomycin in Experimental Pneumonia Caused by Superantigen-Producing Staphylococcus aureus in HLA class II Transgenic Mice.Antimicrob Agents Chemother. 2012 Jul 30. Chemical & Physical Properties Molecular Formula C16H20FN3O4 Exact Mass 337.143799 PSA 71.11000 Index of Refraction 1.554 InChIKey TYZROVQLWOKYKF-ZDUSSCGKSA-N Storage condition Store at RT |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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