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Kasugamycin structure, CAS 19408-46-9

Kasugamycin

CAS Number19408-46-9

SynonymsKASUGAMYCIN HYDROCHLORIDE HYDRATE; MFCD00149375; KASUGAMYCIN HYDROCHL; kasugamycin,monohydrochloride; kasugamycin (jmaff); KASUGAMYCIN HCL HYDRATE; kasumin; KasugaMycin HCl; Kasugamycin Hydrochloride; Kasugamycin hydrochloride from Streptomyces kasugaensis

Molecular FormulaC14H26ClN3O9

Molecular Weight415.82

Purity98%

Density1.97g/cm3

Boiling Point628.2ºC at 760mmHg

Melting Point203ºC (dec)

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9011092 Purity: 98%
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Quality Control of [ 19408-46-9 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number19408-46-9
Catalog No.2A-9011092
Chinese Name春雷霉素盐酸盐
SynonymsKASUGAMYCIN HYDROCHLORIDE HYDRATE; MFCD00149375; KASUGAMYCIN HYDROCHL; kasugamycin,monohydrochloride; kasugamycin (jmaff); KASUGAMYCIN HCL HYDRATE; kasumin; KasugaMycin HCl; Kasugamycin Hydrochloride; Kasugamycin hydrochloride from Streptomyces kasugaensis
Molecular FormulaC14H26ClN3O9
Molecular Weight415.82
Purity98
Density1.97g/cm3
Boiling Point628.2ºC at 760mmHg
Melting Point203ºC (dec)
Appearancepowder
Water SolubilityH2O: soluble
Storage ConditionThe warehouse is ventilated and dried at low tempe
ApplicationKasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic that binds both 30s and 70s ribosomes but not the 50s subunit. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides disr
PubChem ID24896238
MDL NumberMFCD00058459
SMILESC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](N)C[C@@H]1NC(C(O)=O)=N.Cl
InChI1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-;/m1./s1
InChI KeyZDRBJJNXJOSCLR-NZXABURVSA-N
NACRES CodeNA.85
UNSPSC51102829
Hazard SymbolsTransport
MSDSmsds/11092_1_19408_46_9.pdf
BioactivityKasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Schluenzen F, et al. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol. 2006 Oct;13(10):871-8. [2]. Schuwirth BS, et al. Structural analysis of kasugamycin inhibition of translation. Nat Struct Mol Biol. 2006 Oct;13(10):879-86. Chemical & Physical Properties Density 1.97g/cm3 Boiling Point 628.2ºC at 760mmHg Melting Point 203ºC (dec) Molecular Formula C14H26ClN3O9 Molecular Weight 415.824 Flash Point 333.7ºC Exact Mass 415.135742 PSA 218.81000 Vapour Pressure 2.04E-18mmHg at 25°C Index of Refraction 1.738 InChIKey ZDRBJJNXJOSCLR-YZKQBBCCSA-N SMILES CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1N=C(N)C(=O)O.Cl Water Solubility H2O: soluble
Use ofKasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2]. Properties Articles26 Name kasugamycin hydrochloride Synonym More Synonyms Kasugamycin Hydrochloride Biological Activity Description Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Schluenzen F, et al. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol. 2006 Oct;13(10):871-8. [2]. Schuwirth BS, et al. Structural analysis of kasugamycin inhibition of translation. Nat Struct Mol Biol. 2006 Oct;13(10):879-86. Chemical & Physical Properties Exact Mass 415.135742 PSA 218.81000 Index of Refraction 1.738 InChIKey ZDRBJJNXJOSCLR-YZKQBBCCSA-N Water Solubility H2O: soluble
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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