CAS Number521-88-0
SynonymsKaranjin; 3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one; 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one; 3-methoxy-2-phenylfuro[2,3-h]chromen-4-one; MFCD01740600; 3-Methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one
Molecular FormulaC18H12O4
Molecular Weight292.29
Purity≥95.0 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point463.0±45.0 °C at 760 mmHg
Melting Point156ºC
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 521-88-0 |
| Catalog No. | 2A-9011090 |
| Chinese Name | 水黄皮次素 |
| Synonyms | Karanjin; 3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one; 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one; 3-methoxy-2-phenylfuro[2,3-h]chromen-4-one; MFCD01740600; 3-Methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one |
| Molecular Formula | C18H12O4 |
| Molecular Weight | 292.29 |
| Purity | ≥95.0 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 463.0±45.0 °C at 760 mmHg |
| Melting Point | 156ºC |
| Appearance | solid |
| Storage Condition | Store in a cool, dry, well-ventilated warehouse. K |
| Application | Karanjin is the main active furanoflavonol component in Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK. Karanjin can induce cancer cell death throu |
| HTC | 2932999099 |
| MDL Number | MFCD00017406 |
| SMILES | [o]1c2c3c([o]cc3)ccc2[c](c(c1c4ccccc4)OC)=O |
| InChI | 1S/C18H12O4/c1-20-18-15(19)13-7-8-14-12(9-10-21-14)17(13)22-16(18)11-5-3-2-4-6-11/h2-10H,1H3 |
| InChI Key | LKPQNZRGGNOPPU-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/11090_1_521_88_0.pdf |
| Use of | Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2]. Properties Name 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one Synonym More Synonyms Karanjin Biological Activity Description Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2]. Related Catalog Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> AMPK References [1]. Jaiswal N, et al.Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur J Pharmacol. 2011 Nov 16;670(1):22-8. Chemical & Physical Properties Molecular Formula C18H12O4 Exact Mass 292.073547 PSA 52.58000 Index of Refraction 1.678 InChIKey LKPQNZRGGNOPPU-UHFFFAOYSA-N Safety Information RTECS DX1500000 HS Code 2932999099 Precursor & DownStream Precursor 8 CAS#:107521-09-5 (7-hydroxy-3-me... CAS#:89-84-9 2,4-Dihydroxyac... CAS#:38987-00-7 1-(3-Allyl-2,4-... CAS#:69722-46-9 1-(4-HYDROXYBEN... DownStream 1 CAS#:65-85-0 benzoic acid |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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