CAS Number84-16-2
SynonymsSynestrol; meso-3,4-Bis-(4-hydroxy-phenyl)-hexan; Hexoestrolum; hexestrol; Synthovo; Hexron; (R*,S*)-4,4'-(1,2-diethyl-1,2-ethanediyl)bis-phenol; Extra-Plex; Vitestrol; Estronal; Sinestrol; Estrifar; EINECS 201-518-1; 4,4'-(3,4-Hexanediyl)diphenol; MFCD00068996; (R*,S*)-4,4'-(1,2-Diethyl-1,2-ethanediyl)bisphenol; 4,4'-(1,2-Diethylethylene)diphenol; meso-3,4-bis-(4-hydroxyphenyl)hexane; Estra-Plex; 4,4'-hexane-3,4-diyldiphenol; γ,δ-Di(p-hydroxyphenyl)-hexane
Molecular FormulaC18H22O2
Molecular Weight270.37
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point399.5±22.0 °C at 760 mmHg
Melting Point186 °C
Appearancecrystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 84-16-2 |
| Catalog No. | 2A-9010848 |
| Chinese Name | 己烷雌酚 |
| Synonyms | Synestrol; meso-3,4-Bis-(4-hydroxy-phenyl)-hexan; Hexoestrolum; hexestrol; Synthovo; Hexron; (R*,S*)-4,4'-(1,2-diethyl-1,2-ethanediyl)bis-phenol; Extra-Plex; Vitestrol; Estronal; Sinestrol; Estrifar; EINECS 201-518-1; 4,4'-(3,4-Hexanediyl)diphenol; MFCD00068996; (R*,S*)-4,4'-(1,2-Diethyl-1,2-ethanediyl)bisphenol; 4,4'-(1,2-Diethylethylene)diphenol; meso-3,4-bis-(4-hydroxyphenyl)hexane; Estra-Plex; 4,4'-hexane-3,4-diyldiphenol; γ,δ-Di(p-hydroxyphenyl)-hexane |
| Molecular Formula | C18H22O2 |
| Molecular Weight | 270.37 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 399.5±22.0 °C at 760 mmHg |
| Melting Point | 186 °C |
| Appearance | crystalline solid |
| Water Solubility | Water solubility: insoluble; easily soluble in: et |
| Storage Condition | Protect from light and keep airtight. |
| Application | Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used to study diseases caused by estrogen deficiency and can also increase body weight in cattle. |
| MDL Number | C18H22O2 |
| SMILES | CCC(c1ccc(O)cc1)C(CC)c1ccc(O)cc1 |
| InChI | InChI=1S/C18H22O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,17-20H,3-4H2,1-2H3 |
| InChI Key | PBBGSZCBWVPOOL-HDICACEKSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/10848_1_84_16_2.pdf |
| Bioactivity | Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle[1][2]. Related Catalog Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology In Vivo Hexestrol (3 and 6 mg/kg; i.p. once daily for 30 days) has a not significant influence in the ovaries from mice at the dose of 3 mg/kg[2]. Animal Model: Mus musculus (90-120 days, 25-50 g)[2] Dosage: 3, 6 mg/kg (adopted the same dose used to increase weight gain in cattle) Administration: I.p. once daily for 30 days Result: Numerous follicles in different stages of development were found at the dose of 3 mg/kg in the ovaries. Not detected the corpora lutea (CL) at the dose of 6 mg/kg. References [1]. HARDING FE, et, al. The oral use of hexestrol for estrogen deficiency. Am J Obstet Gynecol. 1946 May; 51: 660-5. [2]. Oliveira JM, et, al. Effects of hexestrol on mouse ovarian morphology and ovulation. Maturitas. 2008 Jun 20; 60(2): 153-7. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 399.5±22.0 °C at 760 mmHg Melting Point 186 °C Molecular Formula C18H22O2 Molecular Weight 270.366 Flash Point 181.6±16.9 °C Exact Mass 270.161987 PSA 40.46000 LogP 4.98 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.582 InChIKey PBBGSZCBWVPOOL-HDICACEKSA-N SMILES CCC(c1ccc(O)cc1)C(CC)c1ccc(O)cc1 |
| Use of | Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle[1][2]. Properties Articles25 Name hexestrol Synonym More Synonyms hexestrol Biological Activity Description Hexestrol is a nonsteroidal synthetic estrogen. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle[1][2]. Related Catalog Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology References [1]. HARDING FE, et, al. The oral use of hexestrol for estrogen deficiency. Am J Obstet Gynecol. 1946 May; 51: 660-5. [2]. Oliveira JM, et, al. Effects of hexestrol on mouse ovarian morphology and ovulation. Maturitas. 2008 Jun 20; 60(2): 153-7. Chemical & Physical Properties Molecular Formula C18H22O2 Exact Mass 270.161987 PSA 40.46000 Index of Refraction 1.582 InChIKey PBBGSZCBWVPOOL-HDICACEKSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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