CAS Number23110-15-8
SynonymsFUGILLIN; FUMADIL B; amebacillin; fumagillin; EINECS 245-433-8; MFCD03990453; fumidil; h-3; FUMIDIL B; AMEBACILIN; mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]octan-6-yl]ester; fugilin
Molecular FormulaC26H34O7
Molecular Weight458.54
Purity≥90%
Density1.19g/cm3
Boiling Point608.8ºC at 760mmHg
Melting Point197-198 °C
Appearancepowder
EINECS245-433-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 23110-15-8 |
| Catalog No. | 2A-9010647 |
| Chinese Name | 夫马洁林 |
| Synonyms | FUGILLIN; FUMADIL B; amebacillin; fumagillin; EINECS 245-433-8; MFCD03990453; fumidil; h-3; FUMIDIL B; AMEBACILIN; mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]octan-6-yl]ester; fugilin |
| Molecular Formula | C26H34O7 |
| Molecular Weight | 458.54 |
| Purity | ≥90 |
| Density | 1.19g/cm3 |
| Boiling Point | 608.8ºC at 760mmHg |
| Melting Point | 197-198 °C |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Fumagillin (NSC9168) is extracted from Aspergillus fumigatus and has anti-amoeba activity. |
| EINECS | 245-433-8 |
| HTC | 29419090 |
| PubChem ID | 24894920 |
| MDL Number | MFCD03990453 |
| SMILES | COC1C(CCC2(CO2)C1C3(C)OC3C\C=C(\C)C)OC(=O)\C=C\C=C\C=C\C=C\C(O)=O |
| InChI | 1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+ |
| InChI Key | NGGMYCMLYOUNGM-HCNIIHBUSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/10647_1_23110_15_8.pdf |
| Bioactivity | Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have deterred its acceptance as a viable treatment, but the current body of research on the synthesis of novel analogs of this molecule shows an exciting and promising revival of this drug as both an anti-infective and antiangiogenic agent [1]. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5(4): p. 573-9. Chemical & Physical Properties Density 1.19g/cm3 Boiling Point 608.8ºC at 760mmHg Melting Point >190ºC-192ºC Molecular Formula C26H34O7 Molecular Weight 458.54400 Flash Point 198.8ºC Exact Mass 458.23000 PSA 97.89000 LogP 3.91540 Vapour Pressure 2.7E-16mmHg at 25°C Index of Refraction 1.562 InChIKey NGGMYCMLYOUNGM-UHFFFAOYSA-N SMILES COC1C(OC(=O)C=CC=CC=CC=CC(=O)O)CCC2(CO2)C1C1(C)OC1CC=C(C)C |
| Use of | Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have deterred its acceptance as a viable treatment, but the current body of research on the synthesis of novel analogs of this molecule shows an exciting and promising revival of this drug as both an anti-infective and antiangiogenic agent [1]. Properties Articles30 Name fumagillin Synonym More Synonyms fumagillin Biological Activity Description Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have deterred its acceptance as a viable treatment, but the current body of research on the synthesis of novel analogs of this molecule shows an exciting and promising revival of this drug as both an anti-infective and antiangiogenic agent [1]. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5(4): p. 573-9. Chemical & Physical Properties Molecular Formula C26H34O7 Exact Mass 458.23000 PSA 97.89000 LogP 3.91540 Index of Refraction 1.562 InChIKey NGGMYCMLYOUNGM-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 1648 International Maritime Transport Danger Regulations: 1648 International Air Transport Danger Regulations: 1648 14.2 United Nations shipping name European land transport hazard code: ACETONITRILE, solution IMDG Code: ACETONITRILE, solution IMDG: Acetonitrile, solution 14.3 Transport hazard categories European land transport Dangerous Regulations: 3 International sea transport Dangerous Regulations: 3 International air transport Dangerous Regulations: 3 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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