CAS Number120014-06-4
Synonyms2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-2,3-dihydro-1H-inden-1-one; n-1-one; 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; Aricept; Donepezil hydrochloride monohydrate; (±)-E-2020; 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone; 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; MFCD00912833; donepezil; 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE; 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one; Donezepil; 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-on; D
Molecular FormulaC24H29NO3
Molecular Weight379.49
Purity99%
Density1.1±0.1 g/cm3
Boiling Point527.9±50.0 °C at 760 mmHg
Melting Point207ºC
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 120014-06-4 |
| Catalog No. | 2A-9010227 |
| Chinese Name | 多萘哌齐碱 |
| Synonyms | 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-2,3-dihydro-1H-inden-1-one; n-1-one; 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; Aricept; Donepezil hydrochloride monohydrate; (±)-E-2020; 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone; 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; MFCD00912833; donepezil; 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE; 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one; Donezepil; 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-on; D |
| Molecular Formula | C24H29NO3 |
| Molecular Weight | 379.49 |
| Purity | 99 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 527.9±50.0 °C at 760 mmHg |
| Melting Point | 207ºC |
| Water Solubility | 2.931 mg/L |
| Storage Condition | Room Temperature |
| Application | Donepezil (E 2020) is an AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE respectively. |
| SMILES | N2(CCC(CC2)CC3Cc4c(cc(c(c4)OC)OC)C3=O)Cc1ccccc1 |
| InChI | 1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3 |
| InChI Key | ADEBPBSSDYVVLD-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/10227_1_120014_06_4.pdf |
| Transport Info | Product name: donepezil base |
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