CAS Number129938-20-1
Synonyms(1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropan-1-amine hydrochloride (1:1); (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine hydrochloride; ly 210448 hydrochloride; (S)-N,N-Dimethyl-α-[2-(1-naphthyloxy)ethyl]benzylamine Hydrochloride; (1S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride; (1S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-aminhydrochlorid; (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine hydrochloride (1:1); Dapoxetine HCl; Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, (αS)-, hydrochloride (1:1); (+)-(S)-N,N-Dimethyl-α-(2-(1-naphthyloxy)ethyl)benzylamine hydrochloride; (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine,hydrochloride; MFCD08272809; (S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phen
Molecular FormulaC21H24ClNO
Molecular Weight341.87
Purity≥98 (HPLC)%
Boiling Point454.4ºC at 760 mmHg
Melting Point175-179ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 129938-20-1 |
| Catalog No. | 2A-9010006 |
| Chinese Name | 盐酸达泊西汀 |
| Synonyms | (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropan-1-amine hydrochloride (1:1); (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine hydrochloride; ly 210448 hydrochloride; (S)-N,N-Dimethyl-α-[2-(1-naphthyloxy)ethyl]benzylamine Hydrochloride; (1S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride; (1S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-aminhydrochlorid; (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine hydrochloride (1:1); Dapoxetine HCl; Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, (αS)-, hydrochloride (1:1); (+)-(S)-N,N-Dimethyl-α-(2-(1-naphthyloxy)ethyl)benzylamine hydrochloride; (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine,hydrochloride; MFCD08272809; (S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phen |
| Molecular Formula | C21H24ClNO |
| Molecular Weight | 341.87 |
| Purity | ≥98 (HPLC) |
| Boiling Point | 454.4ºC at 760 mmHg |
| Melting Point | 175-179ºC |
| Appearance | powder |
| Storage Condition | -20°C Freezer |
| Application | Dapoxetine hydrochloride is a short-acting, selective serotonin reuptake inhibitor. |
| HTC | 2922199090 |
| PubChem ID | 329798842 |
| MDL Number | MFCD08272809 |
| SMILES | Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3 |
| InChI | 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1 |
| InChI Key | IHWDIQRWYNMKFM-BDQAORGHSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/10006_1_129938_20_1.pdf |
| Bioactivity | Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).Target: SSRIDapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. Dapoxetine is the only drug with regulatory approval for such an indication. The treatment of PE consists of primarily off-label use of oral selective serotonin reuptake inhibitors (SSRIs) via either on-demand or daily delivery. Related Catalog Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter Research Areas >> Neurological Disease References [1]. McMahon CG. Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51. [2]. Dapoxetine, From Wikipedia, the free encyclopedia Chemical & Physical Properties Boiling Point 454.4ºC at 760 mmHg Melting Point 175-179ºC Molecular Formula C21H24ClNO Molecular Weight 341.874 Flash Point 132.6ºC Exact Mass 341.154633 PSA 12.47000 LogP 5.71360 Vapour Pressure 1.27E-09mmHg at 25°C InChIKey IHWDIQRWYNMKFM-BDQAORGHSA-N SMILES CN(C)C(CCOc1cccc2ccccc12)c1ccccc1.Cl Storage condition -20°C Freezer |
| Use of | Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).Target: SSRIDapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. Dapoxetine is the only drug with regulatory approval for such an indication. The treatment of PE consists of primarily off-label use of oral selective serotonin reuptake inhibitors (SSRIs) via either on-demand or daily delivery. Properties Articles26 Name Dapoxetine Hydrochloride Synonym More Synonyms Dapoxetine Hydrochloride Biological Activity Description Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).Target: SSRIDapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. Dapoxetine is the only drug with regulatory approval for such an indication. The treatment of PE consists of primarily off-label use of oral selective serotonin reuptake inhibitors (SSRIs) via either on-demand or daily delivery. Related Catalog Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter Research Areas >> Neurological Disease References [1]. McMahon CG. Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51. [2]. Dapoxetine, From Wikipedia, the free encyclopedia Chemical & Physical Properties Exact Mass 341.154633 PSA 12.47000 LogP 5.71360 InChIKey IHWDIQRWYNMKFM-BDQAORGHSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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