EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Cloxacillin sodium anhydrous
Cloxacillin sodium anhydrous structure, CAS 642-78-4

Cloxacillin sodium anhydrous

CAS Number642-78-4

SynonymsTegopen; Staphybiotic; Sodium cloxacillin; cloxacillin sodium hydrate; Ankerbin; Cloxapen; Austrastaph; Prevencilina P; Cloxacillin sodium salt hydrate; Sodium cloxacillin monohydrate; cloxacillin sodium monohydrate; Orbenin; MFCD00150735; Prostaphilin A; Ekvacillin; Cloxacillin Sodium Salt; EINECS 211-390-9; Gelstaph; Cloxacillin Sodium

Molecular FormulaC19H17ClN3NaO5S

Molecular Weight457.86

Purity≥95.0 (HPLC)%

Density

Boiling Point

Melting Point170ºC

Flash Point

Appearancepowder or crystals

EINECS211-390-9

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9009887 Purity: ≥95.0 (HPLC)%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 642-78-4 ] Purity: ≥95.0 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number642-78-4
Catalog No.2A-9009887
Chinese Name氯唑西林钠
SynonymsTegopen; Staphybiotic; Sodium cloxacillin; cloxacillin sodium hydrate; Ankerbin; Cloxapen; Austrastaph; Prevencilina P; Cloxacillin sodium salt hydrate; Sodium cloxacillin monohydrate; cloxacillin sodium monohydrate; Orbenin; MFCD00150735; Prostaphilin A; Ekvacillin; Cloxacillin Sodium Salt; EINECS 211-390-9; Gelstaph; Cloxacillin Sodium
Molecular FormulaC19H17ClN3NaO5S
Molecular Weight457.86
Purity≥95.0 (HPLC)
Melting Point170ºC
Appearancepowder or crystals
Water SolubilityH2O: 50 mg/mL, clear, colorless
Storage Condition2-8°C
ApplicationCloxacillin sodium has effective antibacterial activity, with a minimum inhibitory concentration of 256 mg/L against Staphylococcus aureus 25923.
EINECS211-390-9
HTC2941109900
PubChem ID57648259
MDL NumberMFCD00063568
SMILES[Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
InChI1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1
InChI KeySCLZRKVZRBKZCR-SLINCCQESA-M
Beilstein/REAXYS4103180
NACRES CodeNA.85
UNSPSC51102829
MSDSmsds/9887_1_642_78_4.pdf
Use ofProperties Name cloxacillin sodium Synonym More Synonyms Cloxacillin Sodium Biological Activity Related Catalog Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial References [1]. J C Anderson, et al. The Effect of Incorporation of Cloxacillin in Liposomes on Treatment of Experimental Staphylococcal Mastitis in Mice. J Vet Pharmacol Ther. 1986 Sep;9(3):303-9. [2]. W Calame, et al. Influence of Etoposide and Cyclophosphamide on the Efficacy of Cloxacillin and Erythromycin in an Experimental Staphylococcal Infection. Antimicrob Agents Chemother. 1989 Jun;33(6):980-2. Chemical & Physical Properties Exact Mass 475.058075 PSA 140.87000 LogP 1.54280 InChIKey JBJAWVZHLGPBJA-SLINCCQESA-N Stability Stable. Incompatible with strong oxidizing agents. Refrigerate. Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(o-chlorophenyl)-5-methyl- 4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, monosodium salt CAS REGISTRY NUMBER : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C19-H17-C1-N3-O5-S.Na MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T45 ANV ESTJ F1 F1 GVQ CMV- DT5NOJ C1 ER BG &-NA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,322,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,232,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 31,232,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,401,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4495 No. of Facilities: 203 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 4409 (estimated) No. of Female Employees: 2017 (estimated) Safety Information Hazard Codes Xn Safety Phrases S22 WGK Germany 2 RTECS XH8920000 HS Code 2941109900 Synthetic Route Total: 1 Page 6-Aminopenicill... CAS#:551-16-6 3-(2-chlorophen... CAS#:25629-50-9 Cloxacillin Sodium CAS#:642-78-4 2-Chlorobenzaldehyde CAS#:89-98-5 Cloxacillin Sodium CAS#:642-78-4 3-(2-Chlorophen... CAS#:23598-72-3 Cloxacillin Sodium CAS#:642-78-4 Precursor & DownStream Precursor 4 CAS#:551-16-6 6-Aminopenicill... CAS#:25629-50-9 3-(2-chlorophen... CAS#:89-98-5 2-Chlorobenzaldehyde CAS#:23598-72-3 3-(2-Chlorophen... DownStream 0
Transport InfoProduct name: Cloxacillin sodium salt
Related Products in Specialty Chemicals
Closantel57808-65-82A-9009878
Closantel sodium61438-64-02A-9009879
Clothiapine2058-52-82A-9009881
Cloxacepride65569-29-12A-9009884
Cloxacillin benzathine23736-58-52A-9009886
Cloxacillin sodium hydrate7081-44-92A-9009888
Cnidii Fructus PE.2A-3009722A-9009889
Coal tar8007-45-22A-0202239
Cocaethylene529-38-42A-9009891
Cocaine hydrochloride53-21-42A-9009892
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA