CAS Number530-43-8
SynonymsChlorambon; detreopal; CHLORAMPHENICOLPALMITATE,BP; cap-palmitate; Chloramphenicol palmitate; Clorolifarina; chloromycetinpalmitate; Hexadecanoic acid, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester; CHLORAMPHENICAL PALMITATE; (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate; D-threo-(-)-2,2-Dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl)acetamide α-palmitate; EINECS 208-477-9; MFCD00083597; CAP-P; Chloramphenicol palmitate (ester); chloramphenicol 3'-palmitate; (2R,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl palmitate; [R-(R*,R*)]-Hexadecanoic Acid 2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl Ester; Chloropal; D-threo-(-)-2,2-Dichloro-N-(b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl
Molecular FormulaC27H42Cl2N2O6
Molecular Weight561.538
Purity98%
Density1.2±0.1 g/cm3
Boiling Point691.6±55.0 °C at 760 mmHg
Melting Point90ºC
Appearancecrystal, soluble in water
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 530-43-8 |
| Catalog No. | 2A-9009723 |
| Chinese Name | 氯霉素棕榈酸酯 |
| Synonyms | Chlorambon; detreopal; CHLORAMPHENICOLPALMITATE,BP; cap-palmitate; Chloramphenicol palmitate; Clorolifarina; chloromycetinpalmitate; Hexadecanoic acid, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester; CHLORAMPHENICAL PALMITATE; (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate; D-threo-(-)-2,2-Dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl)acetamide α-palmitate; EINECS 208-477-9; MFCD00083597; CAP-P; Chloramphenicol palmitate (ester); chloramphenicol 3'-palmitate; (2R,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl palmitate; [R-(R*,R*)]-Hexadecanoic Acid 2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl Ester; Chloropal; D-threo-(-)-2,2-Dichloro-N-(b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl |
| Molecular Formula | C27H42Cl2N2O6 |
| Molecular Weight | 561.538 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 691.6±55.0 °C at 760 mmHg |
| Melting Point | 90ºC |
| Appearance | crystal, soluble in water |
| Storage Condition | Warehouse low temperature ventilation and drying |
| Application | Chloramphenicol palmitate is an orally active broad-spectrum antibiotic with broad activity against Gram-positive and Gram-negative bacteria. Chloramphenicol palmitate inhibits bacterial protein synth |
| HTC | 29414000 |
| SMILES | CCCCCCCCCCCCCCCC(=O)OCC(NC(=O)C(Cl)Cl)C(O)c1ccc([N+](=O)[O-])cc1 |
| InChI | InChI=1S/C27H42Cl2N2O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-24(32)37-20-23(30-27(34)26(28)29)25(33)21-16-18-22(19-17-21)31(35)36/h16-19,23,25-26,33H,2-15,20H2,1H3,(H,30,34)/t23-,25-/m1/s1 |
| InChI Key | PXKHGMGELZGJQE-ILBGXUMGSA-N |
| MSDS | msds/9723_2_530_43_8.pdf |
| Bioactivity | Chloramphenicol palmitate is an orally active broad spectrum antibiotic and has a broad spectrum of activity against gram positive and gram negative bacteria. Chloramphenicol palmitate inhibits bacterial protein synthesis by blocking the peptidyl transferase step. Chloramphenicol palmitate can be used as bacterial selection agent in transformed cells containing chloramphenicol resistance genes[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Siti Nani Nurbaeti, et al. Sustained-release Microparticle Dry Powders of Chloramphenicol Palmitate or Thiamphenicol Palmitate Prodrugs for Lung Delivery as Aerosols.Eur J Pharm Sci. 2019 Oct 1;138:105028. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 691.6±55.0 °C at 760 mmHg Melting Point 90ºC Molecular Formula C27H42Cl2N2O6 Molecular Weight 561.538 Flash Point 372.1±31.5 °C Exact Mass 560.242004 PSA 121.45000 LogP 9.04 Vapour Pressure 0.0±2.3 mmHg at 25°C Index of Refraction 1.526 InChIKey PXKHGMGELZGJQE-ILBGXUMGSA-N SMILES CCCCCCCCCCCCCCCC(=O)OCC(NC(=O)C(Cl)Cl)C(O)c1ccc([N+](=O)[O-])cc1 |
| Use of | Chloramphenicol palmitate is an orally active broad spectrum antibiotic and has a broad spectrum of activity against gram positive and gram negative bacteria. Chloramphenicol palmitate inhibits bacterial protein synthesis by blocking the peptidyl transferase step. Chloramphenicol palmitate can be used as bacterial selection agent in transformed cells containing chloramphenicol resistance genes[1]. Properties Articles22 Name chloramphenicol palmitate Synonym More Synonyms Chloramphenicol palmitate Biological Activity Description Chloramphenicol palmitate is an orally active broad spectrum antibiotic and has a broad spectrum of activity against gram positive and gram negative bacteria. Chloramphenicol palmitate inhibits bacterial protein synthesis by blocking the peptidyl transferase step. Chloramphenicol palmitate can be used as bacterial selection agent in transformed cells containing chloramphenicol resistance genes[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References Chemical & Physical Properties Exact Mass 560.242004 PSA 121.45000 Index of Refraction 1.526 InChIKey PXKHGMGELZGJQE-ILBGXUMGSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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