CAS Number26973-24-0
SynonymsFalomesin; Celoslin; 7-(1H-Tetrazol-1-yl)acetamido-3-(1,3,4-thiadiazol-2-ylthio)methylceph-3-em-4-carboxylic Acid; Ceftezol; Ceftezole (INN); CG B3Q; CTZ; MFCD00274176; Demethylcefazolin; Ceftezole; Ceftezolo; CG-B 3 Q; Ceftezolum
Molecular FormulaC13H12N8O4S3
Molecular Weight440.481
Purity98%
Density2.1±0.1 g/cm3
Melting Point155ºC (dec.)
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26973-24-0 |
| Catalog No. | 2A-9009674 |
| Chinese Name | 头孢替唑 |
| Synonyms | Falomesin; Celoslin; 7-(1H-Tetrazol-1-yl)acetamido-3-(1,3,4-thiadiazol-2-ylthio)methylceph-3-em-4-carboxylic Acid; Ceftezol; Ceftezole (INN); CG B3Q; CTZ; MFCD00274176; Demethylcefazolin; Ceftezole; Ceftezolo; CG-B 3 Q; Ceftezolum |
| Molecular Formula | C13H12N8O4S3 |
| Molecular Weight | 440.481 |
| Purity | 98 |
| Density | 2.1±0.1 g/cm3 |
| Melting Point | 155ºC (dec.) |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Ceftezole (CTZ) is a broad-spectrum cephem antibiotic with activity against a variety of Gram-positive and Gram-negative bacteria. Ceftezole (CTZ) is a potent alpha-glucosidase inhibitor with antidiab |
| HTC | 3003201400 |
| SMILES | O=C(Cn1cnnn1)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CSC12 |
| InChI | InChI=1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/q;+1/p-1/t8-,11-;/m1./s1 |
| InChI Key | DZMVCVMFETWNIU-LDYMZIIASA-N |
| Use of | Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2]. Properties Name (6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Synonym More Synonyms CTZ Biological Activity Description Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial In Vitro Ceftezole is a broad-spectrum antibiotic, active in vitro against many species of gram-positive and gram-negative bacteria except, Serratia marcescens and Proteus vulgaris[1]. References [1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83. [2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82. Chemical & Physical Properties Molecular Formula C13H12N8O4S3 Exact Mass 440.014374 PSA 234.93000 Index of Refraction 2.003 InChIKey DZMVCVMFETWNIU-LDYMZIIASA-N Storage condition -20℃ Safety Information Hazard Codes T+,N HS Code 3003201400 |
| Transport Info | Product name: Ceftezole |
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