CAS Number1953-02-2
SynonymsSutilan; Thiopronine; EINECS 217-778-4; Capen; SF-572; UNII:C5W04GO61S; Thiosol; Thiora; Thiola; Tioglis; Epatiol; N-(2-Sulfanylpropanoyl)glycine; Tiopronin; Vincol; 2-MPG; MFCD00004861
Molecular FormulaCH3CH(SH)CONHCH2COOH
Molecular Weight163.19
Purity≥98 (TLC)%
Density1.3±0.1 g/cm3
Boiling Point418.3±30.0 °C at 760 mmHg
Melting Point98-100 °C
Appearancepowder
EINECS217-778-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1953-02-2 |
| Catalog No. | 2A-9094122 |
| Chinese Name | 硫普罗宁 |
| Synonyms | Sutilan; Thiopronine; EINECS 217-778-4; Capen; SF-572; UNII:C5W04GO61S; Thiosol; Thiora; Thiola; Tioglis; Epatiol; N-(2-Sulfanylpropanoyl)glycine; Tiopronin; Vincol; 2-MPG; MFCD00004861 |
| Molecular Formula | CH3CH(SH)CONHCH2COOH |
| Molecular Weight | 163.19 |
| Purity | ≥98 (TLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 418.3±30.0 °C at 760 mmHg |
| Melting Point | 98-100 °C |
| Appearance | powder |
| Storage Condition | -20°C Freezer, Under Inert Atmosphere |
| Application | Tiopronin controls the secretion and deposition of cystine in cystinuria. |
| EINECS | 217-778-4 |
| HTC | 2942000000 |
| PubChem ID | 24897101 |
| MDL Number | MFCD00004861 |
| SMILES | CC(S)C(=O)NCC(O)=O |
| InChI | 1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8) |
| InChI Key | YTGJWQPHMWSCST-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1859822 |
| NACRES Code | NA.26 |
| eCl@ss | 32160406 |
| UNSPSC | 12352209 |
| Hazard Symbols | transportation |
| MSDS | msds/94122_1_1953_02_2.pdf |
| Bioactivity | Tiopronin is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria.Target: OthersTiopronin is used primarily for cystinuria and is well known in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis, though tiopronin is not an anti-inflammatory. Tiopronin is also sometimes used as a stabilizing agent for metal nanoparticles. The thiol group binds to the nanoparticles, preventing coagulation [1, 2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Others References [1]. http://en.wikipedia.org/wiki/Tiopronin [2]. Dahl, J.A., B.L. Maddux, and J.E. Hutchison, Toward greener nanosynthesis. Chem Rev, 2007. 107(6): p. 2228-69. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 418.3±30.0 °C at 760 mmHg Melting Point 93-98 °C Molecular Formula C5H9NO3S Molecular Weight 163.195 Flash Point 206.8±24.6 °C Exact Mass 163.030319 PSA 105.20000 LogP -0.33 Vapour Pressure 0.0±2.1 mmHg at 25°C Index of Refraction 1.519 InChIKey YTGJWQPHMWSCST-UHFFFAOYSA-N SMILES CC(S)C(=O)NCC(=O)O Storage condition -20°C Freezer, Under Inert Atmosphere |
| Use of | Tiopronin is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria.Target: OthersTiopronin is used primarily for cystinuria and is well known in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis, though tiopronin is not an anti-inflammatory. Tiopronin is also sometimes used as a stabilizing agent for metal nanoparticles. The thiol group binds to the nanoparticles, preventing coagulation [1, 2]. Properties Articles36 Name Tiopronin Synonym More Synonyms Tiopronin Biological Activity Description Tiopronin is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria.Target: OthersTiopronin is used primarily for cystinuria and is well known in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis, though tiopronin is not an anti-inflammatory. Tiopronin is also sometimes used as a stabilizing agent for metal nanoparticles. The thiol group binds to the nanoparticles, preventing coagulation [1, 2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Natural Products >> Others References [1]. http://en.wikipedia.org/wiki/Tiopronin [2]. Dahl, J.A., B.L. Maddux, and J.E. Hutchison, Toward greener nanosynthesis. Chem Rev, 2007. 107(6): p. 2228-69. Chemical & Physical Properties Molecular Formula C5H9NO3S Exact Mass 163.030319 PSA 105.20000 LogP -0.33 Index of Refraction 1.519 InChIKey YTGJWQPHMWSCST-UHFFFAOYSA-N SMILES CC(S)C(=O)NCC(=O)O |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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