| Chemical & Physical Properties | |
|---|---|
| CAS Number | 120068-36-2 |
| Catalog No. | 2A-9093788 |
| Chinese Name | 氟虫腈砜 |
| Synonyms | Fipronil sulfone; FIPRONIL-SULFONE; T5NNJ AR BG FG DXFFF& CCN DSWXFFF EZ |
| Molecular Formula | C12H4Cl2F6N4O2S |
| Molecular Weight | 453.15 |
| Purity | 98.00 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 531.6±50.0 °C at 760 mmHg |
| Storage Condition | Room temperature, airtight, dry |
| Application | Fipronil sulfone is the major metabolite of fipronil. Fipronil sulfone selectively inhibits GABA receptors with an IC50 of 175 nM (determined from the noncompetitive blocker site ([3H]EBOB)). |
| PubChem ID | 9469776 |
| SMILES | N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(=O)(=O)C(F)(F)F |
| InChI | InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 |
| InChI Key | LGHZJDKSVUTELU-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site). Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor References [1]. D Hainzl,et al. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chem Res Toxicol . 1998 Dec;11(12):1529-35. Chemical & Physical Properties Density 1.9±0.1 g/cm3 Boiling Point 531.6±50.0 °C at 760 mmHg Molecular Formula C12H4Cl2F6N4O2S Molecular Weight 453.147 Flash Point 275.3±30.1 °C Exact Mass 451.933624 PSA 110.15000 LogP 7.44 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.592 InChIKey LGHZJDKSVUTELU-UHFFFAOYSA-N SMILES N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(=O)(=O)C(F)(F)F |
| Use of | Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site). Properties Name fipronil-sulfone Synonym More Synonyms FIPRONIL-SULFONE Biological Activity Description Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits?GABA receptor?with?IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site). Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor References [1]. D Hainzl,et al. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chem Res Toxicol . 1998 Dec;11(12):1529-35. Chemical & Physical Properties Exact Mass 451.933624 PSA 110.15000 Index of Refraction 1.592 InChIKey LGHZJDKSVUTELU-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Fipronil sulfone) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (Fipronil sulfone) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Fipronil sulfone) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations International Air Transport Dangerous Regulations: No Marine Pollutants (Yes/No): Yes 14.6 Special reminder to users No data available |
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