
CAS Number13755-38-9
SynonymsSodium nitroprusside; EINECS 238-373-9; Nitroprusside sodium; Sodium nitroferricyanide(III) dihydrate; Sodium nitroferricyanide dihydrate; SODIUM NITROPRUSSIDE DIHYDRATE; MFCD00149192; sodium pentacyanidonitrosylferrate(III) dihydrate; Nipridedihydrate; Sodium pentacyanonitrosylferrate dihydrate; Sodium pentacyanonitrosylferrate; Sodium Nitropr; Nitroprusside (disodium dihydrate)
Molecular FormulaNa2[Fe(CN)5NO] · 2H2O
Molecular Weight297.95
Purity≥99%
Density1.72
Appearancecrystals or chunks
EINECS238-373-9
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13755-38-9 |
| Catalog No. | 2A-9093723 |
| Chinese Name | 硝普钠 |
| Synonyms | Sodium nitroprusside; EINECS 238-373-9; Nitroprusside sodium; Sodium nitroferricyanide(III) dihydrate; Sodium nitroferricyanide dihydrate; SODIUM NITROPRUSSIDE DIHYDRATE; MFCD00149192; sodium pentacyanidonitrosylferrate(III) dihydrate; Nipridedihydrate; Sodium pentacyanonitrosylferrate dihydrate; Sodium pentacyanonitrosylferrate; Sodium Nitropr; Nitroprusside (disodium dihydrate) |
| Molecular Formula | Na2[Fe(CN)5NO] · 2H2O |
| Molecular Weight | 297.95 |
| Purity | ≥99 |
| Density | 1.72 |
| Appearance | crystals or chunks |
| Water Solubility | 400g/l (slow decomposition) |
| Storage Condition | Sealed at room temperature, cool, ventilated and d |
| Packaging | III |
| Application | Sodium nitroprusside dihydrate is a vasodilator that promotes the release of NO into the blood. |
| EINECS | 238-373-9 |
| HTC | 2837199090 |
| PubChem ID | 329763522 |
| MDL Number | MFCD00149192 |
| SMILES | O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N |
| InChI | 1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;; |
| InChI Key | OIRZWVYIQXBRFC-UHFFFAOYSA-N |
| NACRES Code | NB.24 |
| UNSPSC | 12352300 |
| Hazard Symbols | 6.1 |
| MSDS | msds/93723_1_13755_38_9.pdf |
| Bioactivity | Nitroprusside disodium dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.Target: OthersNitroprusside disodium dihydrate is a potent vasodilator. Sodium nitroprusside has potent vasodilating effects in arterioles and venules. Sodium Nitroprusside breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate [1]. Sodium nitroprusside decreases the proliferation of vascular smooth muscle cells [2]. Sodium nitroprusside (5 mg/kg) significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats [3]. Related Catalog Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Cardiovascular Disease References [1]. Wink, D.A., et al., The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch Biochem Biophys, 1996. 331(2): p. 241-8. [2]. Garg, U.C. and A. Hassid, Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest, 1989. 83(5): p. 1774-7. [3]. Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63(3): p. 405. Chemical & Physical Properties Density 1.72 Molecular Formula C5H4FeN6Na2O3 Molecular Weight 297.948 Exact Mass 297.948975 PSA 166.84000 LogP 0.16990 InChIKey XRKMNJXYOFSTBE-UHFFFAOYSA-N SMILES O.O.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+4].[N-]=O.[Na+].[Na+] Storage condition Store at RT. Water Solubility 400g/l (slow decomposition) |
| Use of | Properties Articles86 Name sodium nitroprusside dihydrate Synonym More Synonyms Sodium nitroprusside dihydrate Biological Activity Related Catalog Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Cardiovascular Disease References [1]. Wink, D.A., et al., The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch Biochem Biophys, 1996. 331(2): p. 241-8. [2]. Garg, U.C. and A. Hassid, Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest, 1989. 83(5): p. 1774-7. [3]. Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63(3): p. 405. Chemical & Physical Properties Molecular Formula C5H4FeN6Na2O3 Exact Mass 297.948975 PSA 166.84000 LogP 0.16990 InChIKey XRKMNJXYOFSTBE-UHFFFAOYSA-N SMILES O.O.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+4].[N-]=O.[Na+].[Na+] Storage condition Store at RT. |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Danger Regulations: 3288 International Maritime Danger Regulations: 3288 International Air Transport Danger Regulations: 3288 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, INORGANIC, N.O.S. (Sodium nitroferricyanide(III) dihydrate) IMDG: TOXIC SOLID, INORGANIC, N.O.S. (Sodium nitroferricyanide(III) dihydrate) International air transport hazard regulations: Toxic solid, inorganic, n.o.s. (Sodium nitroferricyanide(III) dihydrate) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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