| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2179-37-5 |
| Catalog No. | 2A-9009329 |
| Chinese Name | 平痉可宁 |
| Synonyms | Benzcyclan; EINECS 218-547-0; BENCYCLANE; Benzcyclane |
| Molecular Formula | C19H31O1N1 |
| Molecular Weight | 289.46 |
| Purity | 98.00 |
| Density | 0.97g/cm3 |
| Boiling Point | 384.2ºC at 760mmHg |
| Storage Condition | 2-8℃ |
| Application | Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and vasodilator effective in the treatment of various peripheral circulatory disorders. |
| HTC | 2922199090 |
| MDL Number | MFCD00868310 |
| SMILES | CN(C)CCCOC1(Cc2ccccc2)CCCCCC1 |
| InChI | InChI=1S/C19H31NO/c1-20(2)15-10-16-21-19(13-8-3-4-9-14-19)17-18-11-6-5-7-12-18/h5-7,11-12H,3-4,8-10,13-17H2,1-2H3 |
| InChI Key | FYJJXENSONZJRG-UHFFFAOYSA-N |
| MSDS | msds/9329_1_2179_37_5.pdf |
| Use of | Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders. Properties Name 3-(1-benzylcycloheptyl)oxy-N,N-dimethylpropan-1-amine Synonym More Synonyms Benzcyclane Biological Activity Description Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease In Vivo Benzcyclane, although capable of aggregating platelets by itself at very high concentrations, shows a striking inhibitory effect, over a wide range of concentrations, both on platelet aggregation induced by ADP, epinephrine or collagen and on platelet adhesiveness to glass or collagen. Clot retraction is also clearly inhibited[1]. Benzcyclane induces use-dependent inhibition of Na channels in muscle, similarly as do class 1 antiarrhytnmic drugs. Inhibition was observed with both normal and cevadine-modified Na channels[2]. References [1]. Ponari O, et al. In vitro effects of bencyclan on coagulation, fibrinolysis and platelet function. Arzneimittelforschung. 1976;26(8):1532-8. [2]. Nánási PP, et al. Effects of bencyclane on normal and cevadine-modified Na channels in frog skeletal muscle. Gen Physiol Biophys. 1989 Oct;8(5):447-58. Chemical & Physical Properties Molecular Formula C19H31NO Exact Mass 289.24100 PSA 12.47000 LogP 4.29040 Index of Refraction 1.52 InChIKey FYJJXENSONZJRG-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2922199090 Synthetic Route Total: 1 Page Cycloheptanol,1... CAS#:4006-73-9 3-Chloro-N,N-di... CAS#:109-54-6 Benzcyclane CAS#:2179-37-5 Literature: Pallos; Budai; Zolyomi Arzneimittel-Forschung, 1972 , vol. 22, # 9 p. 1502 - 1505 Precursor & DownStream Precursor 2 CAS#:4006-73-9 Cycloheptanol,1... CAS#:109-54-6 3-Chloro-N,N-di... DownStream 1 CAS#:22671-53-0 3-(1-benzylcycl... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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