CAS Number6398-98-7
SynonymsAmodiaquine hydrochloride USP24; Amodiaquin dihydrochloride dihydrate; AMODIAQUIN DIHYDROCHLORIDE DIHYDATE; MFCD00078857; Amodiaquin hydrochloride dihydrate; AMODIAQUIN HYDROCHLORIDE; AMODIAQUINE 2HCL DIHYDRATE; EINECS 200-706-0; Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride, hydrate (1:2:2); AMODIAQUIN DIHYDROCHLORIDE; AMODIAQUINE HCL; 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol dihydrochloride dihydrate; AMODIAQUINE DIHYDROCHLORIDE
Molecular FormulaC20H22ClN3O.2H2O.2HCl
Molecular Weight464.81
Purity98%
Boiling Point535.4ºC at 760 mmHg
AppearanceSolid;White to Yellow to Orange powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6398-98-7 |
| Catalog No. | 2A-9009171 |
| Chinese Name | 阿莫地喹盐酸盐 |
| Synonyms | Amodiaquine hydrochloride USP24; Amodiaquin dihydrochloride dihydrate; AMODIAQUIN DIHYDROCHLORIDE DIHYDATE; MFCD00078857; Amodiaquin hydrochloride dihydrate; AMODIAQUIN HYDROCHLORIDE; AMODIAQUINE 2HCL DIHYDRATE; EINECS 200-706-0; Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride, hydrate (1:2:2); AMODIAQUIN DIHYDROCHLORIDE; AMODIAQUINE HCL; 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol dihydrochloride dihydrate; AMODIAQUINE DIHYDROCHLORIDE |
| Molecular Formula | C20H22ClN3O.2H2O.2HCl |
| Molecular Weight | 464.81 |
| Purity | 98 |
| Boiling Point | 535.4ºC at 760 mmHg |
| Appearance | Solid;White to Yellow to Orange powder to crystal |
| Water Solubility | Water solubility: soluble; soluble in: methanol; v |
| Storage Condition | Keep away from light, cool and dry place, sealed a |
| Application | Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor used as an antimalarial and anti-inflammatory agent. |
| PubChem ID | 329749016 |
| MDL Number | MFCD00078857 |
| SMILES | O.Cl.CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O |
| InChI | 1S/C20H22ClN3O.ClH.H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);1H;1H2 |
| InChI Key | AOFIMJMWPZOPAJ-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9171_1_6398_98_7.pdf |
| Bioactivity | Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. Related Catalog Signaling Pathways >> Epigenetics >> Histone Methyltransferase Research Areas >> Inflammation/Immunology Chemical & Physical Properties Boiling Point 535.4ºC at 760 mmHg Molecular Formula C20H22ClN3O.2H2O.2HCl Molecular Weight 464.81 Flash Point 277.6ºC PSA 48.39000 LogP 6.85620 InChIKey YVNAYSHNIILOJS-UHFFFAOYSA-N SMILES CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O.Cl.Cl.O.O |
| Use of | Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. Properties Name amodiaquine hydrochloride Synonym More Synonyms Amodiaquin dihydrochloride dihydrate Biological Activity Description Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. Related Catalog Signaling Pathways >> Epigenetics >> Histone Methyltransferase Research Areas >> Inflammation/Immunology Chemical & Physical Properties PSA 48.39000 LogP 6.85620 InChIKey YVNAYSHNIILOJS-UHFFFAOYSA-N |
| Transport Info | Product name: Amodiaquine hydrochloride |
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