CAS Number177834-92-3
Synonyms1H-indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-, monohydrobromide; Relert; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole monohydrobromide; ELETRIPTAN HBR; (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole hydrobromide; 3-{[(2R)-1-méthylpyrrolidin-2-yl]méthyl}-5-[2-(phénylsulfonyl)éthyl]-1H-indole bromhydrate; (R)-3-[(1-methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide salt; 3-{[(2R)-1-Methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indolhydrobromid; 1H-Indole,3-(((2R)-1-methyl-2-pyrrolidinyl))methyl)-5-(2-(phenylsulfonyl)ethyl)-,monohydrobromide; 3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide; 3-{[(2R)-1-Methyl
Molecular FormulaC22H27BrN2O2S
Molecular Weight463.43
Purity≥98 (HPLC)%
Boiling Point633.9ºC at 760 mmHg
Melting Point169-171ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 177834-92-3 |
| Catalog No. | 2A-9091580 |
| Chinese Name | 依来曲普坦氢溴酸盐 |
| Synonyms | 1H-indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-, monohydrobromide; Relert; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole monohydrobromide; ELETRIPTAN HBR; (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole hydrobromide; 3-{[(2R)-1-méthylpyrrolidin-2-yl]méthyl}-5-[2-(phénylsulfonyl)éthyl]-1H-indole bromhydrate; (R)-3-[(1-methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide salt; 3-{[(2R)-1-Methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indolhydrobromid; 1H-Indole,3-(((2R)-1-methyl-2-pyrrolidinyl))methyl)-5-(2-(phenylsulfonyl)ethyl)-,monohydrobromide; 3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide; 3-{[(2R)-1-Methyl |
| Molecular Formula | C22H27BrN2O2S |
| Molecular Weight | 463.43 |
| Purity | ≥98 (HPLC) |
| Boiling Point | 633.9ºC at 760 mmHg |
| Melting Point | 169-171ºC |
| Appearance | powder |
| Water Solubility | DMSO: >10mg/mL |
| Storage Condition | Desiccate at RT |
| HTC | 2933990090 |
| PubChem ID | 7849035 |
| MDL Number | MFCD08141806 |
| SMILES | Br.CN1CCCC1Cc2c[nH]c3ccc(CCS(=O)(=O)c4ccccc4)cc23 |
| InChI | 1S/C22H26N2O2S.BrH/c1-24-12-5-6-19(24)15-18-16-23-22-10-9-17(14-21(18)22)11-13-27(25,26)20-7-3-2-4-8-20;/h2-4,7-10,14,16,19,23H,5-6,11-13,15H2,1H3;1H/t19-;/m1./s1 |
| InChI Key | UTINOWOSWSPFLJ-FSRHSHDFSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/91580_1_177834_92_3.pdf |
| Use of | Properties Name eletriptan hydrobromide Synonym More Synonyms Eletriptan HBr Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease References [1]. Napier C, et al. Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors. Eur J Pharmacol, 1999, 368(2-3), 259-268. [2]. MaassenVanDenBrink A, et al. Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels. Neurology, 2000, 55(10), 1524-1530. [3]. Gupta P, et al. The in vivo pharmacological profile of eletriptan (UK-116,044): a potent and novel 5-HT(1B/1D) receptor agonist. Eur J Pharmacol, 2000, 398(1), 73-81. [4]. Hoskin KL, et al. The 5-hydroxytryptamine1B/1D/1F receptor agonists eletriptan and naratriptan inhibit trigeminovascular input to the nucleus tractus solitarius in the cat. Brain Res, 2004, 998(1), 91-99. Chemical & Physical Properties Molecular Formula C22H27BrN2O2S PSA 61.55000 LogP 4.83970 InChIKey UTINOWOSWSPFLJ-FSRHSHDFSA-N Storage condition Desiccate at RT Safety Information Signal Word Warning Hazard Statements H319 Precautionary Statements P305 + P351 + P338 Hazard Codes Xi Risk Phrases 36 Safety Phrases 26 RIDADR NONH for all modes of transport HS Code 2933990090 Synthetic Route (R)-3-((1-METHY... 180637-89-2 Eletriptan HBr 177834-92-3 (R)-5-(2-phenyl... 143577-60-0 Eletriptan HBr 177834-92-3 Eletriptan 143322-58-1 Eletriptan HBr 177834-92-3 Precursor & DownStream Precursor 9 CAS#:180637-89-2 (R)-3-((1-METHY... CAS#:143577-60-0 (R)-5-(2-phenyl... CAS#:143322-58-1 Eletriptan CAS#:143322-57-0 (R)-5-Bromo-3-(... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Plastic & Specialty Additives | ||
|---|---|---|
| 6-bromo-3-iodopyridin-2-amine | 1245643-34-8 | 2A-9089310 |
| 2-chloro-5-(trifluoromethyl)-6-iodopyridine | 518057-64-2 | 2A-9090563 |
| 1-Benzoyl-4-iodopyrazol | 116228-38-7 | 2A-9090569 |
| TRIPROLIDINE HCL | 550-70-9 | 2A-9091493 |
| (3-ACRYLAMIDOPROPYL)TRIMETHYLAMMONIUM CHLORIDE | 45021-77-0 | 2A-9091519 |
| TRIPHENYLARSINE OXIDE | 1153-05-5 | 2A-9091801 |
| 5-Bromo-2-fluoro-3-iodopyridine | 1214376-88-1 | 2A-9092194 |
| IODOPHOR | 392-86-4 | 2A-9092523 |
| n-Hexyl-triphenylphosphonium bromide | 4762-26-9 | 2A-9092583 |
| n-Octyl triphenylphosphonium bromide | 42036-78-2 | 2A-9092584 |
| Browse all Plastic & Specialty Additives products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS