Albendazole structure, CAS 54965-21-8

Albendazole

CAS Number54965-21-8

SynonymsCarbamic acid, N-[5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; Methyl hydrogen [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbonimidate; SKF62979; Bilutac; MFCD00083232; ALBEN; Atasol; carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; SK&F-62979; ZENTEL; SK&F 62979; ALBENZA; EINECS 259-414-7; methyl-5-propylthio-2-benzimidazole carbamate; Bruzol; methyl N-[5-(propylthio)-1H-benzimidazol-2-yl]carbamate; Albendazole; ZEBEN; methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate; methyl 5-(propylthio)benzimidazol-2-ylcarbamate; 5-propylthio-2-carbomethoxyaminobenzimidazole; Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; methyl [5-(propylsulfanyl)-1H-1,3-benzimidazol-2-yl]carbamate; Monil; SK&F62979

Molecular FormulaC12H15N3O2S

Molecular Weight265.33

Purity98%

Density1.3±0.1 g/cm3

Boiling Point

Melting Point207-211°C(分解)

Flash Point

AppearanceWhite to light yellow crystalline powder, odorless.

EINECS259-414-7

MSDSChineseEnglish

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Cat. No.: 2A-9009089 Purity: 98%
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Quality Control of [ 54965-21-8 ] Purity: 98% SDS Specification MoL

Chemical & Physical Properties
CAS Number54965-21-8
Catalog No.2A-9009089
Chinese Name阿苯达唑
SynonymsCarbamic acid, N-[5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; Methyl hydrogen [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbonimidate; SKF62979; Bilutac; MFCD00083232; ALBEN; Atasol; carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; SK&F-62979; ZENTEL; SK&F 62979; ALBENZA; EINECS 259-414-7; methyl-5-propylthio-2-benzimidazole carbamate; Bruzol; methyl N-[5-(propylthio)-1H-benzimidazol-2-yl]carbamate; Albendazole; ZEBEN; methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate; methyl 5-(propylthio)benzimidazol-2-ylcarbamate; 5-propylthio-2-carbomethoxyaminobenzimidazole; Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; methyl [5-(propylsulfanyl)-1H-1,3-benzimidazol-2-yl]carbamate; Monil; SK&F62979
Molecular FormulaC12H15N3O2S
Molecular Weight265.33
Purity98
Density1.3±0.1 g/cm3
Melting Point207-211°C(分解)
AppearanceWhite to light yellow crystalline powder, odorless.
Water SolubilitySlightly soluble in organic solvents, insoluble in
Storage ConditionSealed, stored at 0-6ºC
ApplicationAlbendazole is a benzimidazole compound that can fight worm infections.
EINECS259-414-7
HTC3004909090
PubChem ID329823277
MDL NumberMFCD00083232
SMILESCCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
InChI1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI KeyHXHWSAZORRCQMX-UHFFFAOYSA-N
NACRES CodeNA.24
UNSPSC41116107
Hazard SymbolsTransport
MSDSmsds/9089_1_54965_21_8.pdf
BioactivityAlbendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations. Food and Drug Administration (FDA) has not approved albendazole for this indication. It is marketed by Amedra Pharmaceuticals. Albendazole was first discovered at the SmithKline Animal Health Laboratories in 1972. It is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of domestic animals and humans.Albendazole has been used as an anthelmintic and for control of flukes in a variety of animal species, including cattle, sheep, goats, swine, camels, dogs, cats, elephants, poultry and others. In many countries, it is very commonly used for ruminant livestock. For use in livestock, albendazole is marketed by Zoetis (formerly Pfizer Animal Health) in numerous countries (including the United States and Canada) as Valbazen in oral suspension and paste formulations; by Interchemie in the Netherlands and elsewhere as Albenol-100; by Channelle Animal Health Ltd. in the United Kingdom as Albex; by Ravensdown in New Zealand as Albendazole; etc. Although most formulations are administered orally, Ricomax (ricobendazole, or albendazole sulfoxide) is administered by subcutaneous injection. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Theodorides VJ, et al. Anthelmintic activity of albendazole against liver flukes, tapeworms., lung and gastrointestinal roundworms. Experientia. 1976 Jun 15;32(6):702-3. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Melting Point 207-211°C (decomposition) Molecular Formula C12H15N3O2S Molecular Weight 265.331 Exact Mass 265.088501 PSA 92.31000 LogP 3.07 Index of Refraction 1.634 InChIKey HXHWSAZORRCQMX-UHFFFAOYSA-N SMILES CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1 Storage condition 0-6°C
Use ofAlbendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.Target: AntiparasiticAlbendazole, marketed as Albenza (United States), Eskazole, Zentel, Andazol and Alworm, is a benzimidazole drug used for the treatment of a variety of parasitic worm infestations. Although this use is widespread in the United States, the U.S. Food and Drug Administration (FDA) has not approved albendazole for this indication. It is marketed by Amedra Pharmaceuticals. Albendazole was first discovered at the SmithKline Animal Health Laboratories in 1972. It is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of domestic animals and humans.Albendazole has been used as an anthelmintic and for control of flukes in a variety of animal species, including cattle, sheep, goats, swine, camels, dogs, cats, elephants, poultry and others. In many countries, it is very commonly used for ruminant livestock. For use in livestock, albendazole is marketed by Zoetis (formerly Pfizer Animal Health) in numerous countries (including the United States and Canada) as Valbazen in oral suspension and paste formulations; by Interchemie in the Netherlands and elsewhere as Albenol-100; by Channelle Animal Health Ltd. in the United Kingdom as Albex; by Ravensdown in New Zealand as Albendazole; etc. Although most formulations are administered orally, Ricomax (ricobendazole, or albendazole sulfoxide) is administered by subcutaneous injection. Properties Articles124 Name albendazole Synonym More Synonyms Albendazole Biological Activity Description Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.Target: AntiparasiticAlbendazole, marketed as Albenza (United States), Eskazole, Zentel, Andazol and Alworm, is a benzimidazole drug used for the treatment of a variety of parasitic worm infestations. Although this use is widespread in the United States, the U.S. Food and Drug Administration (FDA) has not approved albendazole for this indication. It is marketed by Amedra Pharmaceuticals. Albendazole was first discovered at the SmithKline Animal Health Laboratories in 1972. It is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of domestic animals and humans.Albendazole has been used as an anthelmintic and for control of flukes in a variety of animal species, including cattle, sheep, goats, swine, camels, dogs, cats, elephants, poultry and others. In many countries, it is very commonly used for ruminant livestock. For use in livestock, albendazole is marketed by Zoetis (formerly Pfizer Animal Health) in numerous countries (including the United States and Canada) as Valbazen in oral suspension and paste formulations; by Interchemie in the Netherlands and elsewhere as Albenol-100; by Channelle Animal Health Ltd. in the United Kingdom as Albex; by Ravensdown in New Zealand as Albendazole; etc. Although most formulations are administered orally, Ricomax (ricobendazole, or albendazole sulfoxide) is administered by subcutaneous injection. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Theodorides VJ, et al. Anthelmintic activity of albendazole against liver flukes, tapeworms., lung and gastrointestinal roundworms. Experientia. 1976 Jun 15;32(6):702-3. Chemical & Physical Properties Molecular Formula C12H15N3O2S Exact Mass 265.088501 PSA 92.31000 Index of Refraction 1.634 InChIKey HXHWSAZORRCQMX-UHFFFAOYSA-N
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Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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