CAS Number1162-65-8
SynonymsAflatoxin B1; (-)-Aflatoxin B1; (6aR,9aS)-4-Methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; Aflatoxin B1, crystalline; MFCD00869647; Aflatoxin; EINECS 214-603-3
Molecular FormulaC17H12O6
Molecular Weight312.27
Purity≥98.0 (HPLC)%
Density1.6±0.1 g/cm3
Boiling Point528.2±50.0 °C at 760 mmHg
Melting Point268-269 °C
Appearancepowder
EINECS214-603-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1162-65-8 |
| Catalog No. | 2A-9009072 |
| Chinese Name | 黄曲霉素 B1 |
| Synonyms | Aflatoxin B1; (-)-Aflatoxin B1; (6aR,9aS)-4-Methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; Aflatoxin B1, crystalline; MFCD00869647; Aflatoxin; EINECS 214-603-3 |
| Molecular Formula | C17H12O6 |
| Molecular Weight | 312.27 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 528.2±50.0 °C at 760 mmHg |
| Melting Point | 268-269 °C |
| Appearance | powder |
| Storage Condition | Store sealed at 0ºC-4ºC |
| Packaging | I |
| Application | Aflatoxin B1 (AFB1) is a class 1A carcinogen and a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) causes mutations mainly by inducing the G-->T at the third positio |
| EINECS | 214-603-3 |
| PubChem ID | 24891116 |
| MDL Number | MFCD00869647 |
| SMILES | COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCC5=O)c14 |
| InChI | 1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1 |
| InChI Key | OQIQSTLJSLGHID-WNWIJWBNSA-N |
| Beilstein/REAXYS | 1269174 |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/9072_1_1162_65_8.pdf |
| Bioactivity | Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Target Human Endogenous Metabolite References [1]. Gizachew D, et al. Aflatoxin B1 (AFB1) production by Aspergillus flavus and Aspergillus parasiticus on ground Nyjer seeds: The effect of water activity and temperature. Int J Food Microbiol. 2019 May 2;296:8-13. [2]. Aguilar F, et al. Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8586-90. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 528.2±50.0 °C at 760 mmHg Melting Point 268-269 °C Molecular Formula C17H12O6 Molecular Weight 312.274 Flash Point 237.7±30.2 °C Exact Mass 312.063385 PSA 74.97000 LogP 0.45 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.687 InChIKey OQIQSTLJSLGHID-WNWIJWBNSA-N SMILES COc1cc2c(c3oc(=O)c4c(c13)CCC4=O)C1C=COC1O2 |
| Use of | Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2]. Properties Articles123 Name aflatoxin B1 Synonym More Synonyms AFLATOXIN B1 Biological Activity Description Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Human Endogenous Metabolite References [1]. Gizachew D, et al. Aflatoxin B1 (AFB1) production by Aspergillus flavus and Aspergillus parasiticus on ground Nyjer seeds: The effect of water activity and temperature. Int J Food Microbiol. 2019 May 2;296:8-13. [2]. Aguilar F, et al. Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8586-90. Chemical & Physical Properties Molecular Formula C17H12O6 Exact Mass 312.063385 PSA 74.97000 Index of Refraction 1.687 InChIKey OQIQSTLJSLGHID-WNWIJWBNSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3462 International Maritime Transport Danger Regulations: 3462 International Air Transport Danger Regulations: 3462 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXINS EXTRAC TED FROM LIVING SOURCES, SOLID, N.O.S. (Aflatoxin B1) IMDG: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S. (Aflatoxin B1) International Air Transport Risk Regulations: Toxins, extracted from living sources, solid, n.o.s. (Aflatoxin B1) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Dangerous Regulations for land transport: I International Dangerous Regulations for sea transport: I International Dangerous Regulations for air transport: I 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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