CAS Number29741-10-4
Synonymsluteolin 7-O-beta-D-glucosiduronic acid; Luteolin-7-glucuronide; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid; Luteolin 7-O-glucuronide
Molecular FormulaC21H18O12
Molecular Weight462.36
Density1.8±0.1 g/cm3
Boiling Point892.5±65.0 °C at 760 mmHg
Melting Point242-244℃
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 29741-10-4 |
| Catalog No. | 2A-9089959 |
| Chinese Name | 木犀草素-7-O-葡萄糖醛酸苷 |
| Synonyms | luteolin 7-O-beta-D-glucosiduronic acid; Luteolin-7-glucuronide; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid; Luteolin 7-O-glucuronide |
| Molecular Formula | C21H18O12 |
| Molecular Weight | 462.36 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 892.5±65.0 °C at 760 mmHg |
| Melting Point | 242-244℃ |
| Storage Condition | ?20°C |
| Application | Luteolin 7-O-glucuronide can be used as an effective free radical scavenger and can inhibit the activity of matrix metalloproteinases (MMPs). Its IC50 values for MMP-1, MMP-3, MMP-8, MMP-9, and MMP- |
| SMILES | O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)c(O)c4 |
| InChI | 1S/C21H18O12/c22-9-2-1-7(3-10(9)23)13-6-12(25)15-11(24)4-8(5-14(15)32-13)31-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-24,26-28H,(H,29,30)/t16-,17-,18+,19-,21?/m0/s1 |
| InChI Key | VSUOKLTVXQRUSG-DAZJWRSOSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 85151701 |
| Hazard Symbols | transportation |
| MSDS | msds/89959_1_29741_10_4.pdf |
| Bioactivity | Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. Related Catalog Research Areas >> Others Natural Products >> Flavonoids Target MMP-1:17.63 μM (IC50) MMP-3:7.99 μM (IC50) MMP-8:11.42 μM (IC50) MMP-9:12.85 μM (IC50) MMP13:0.03 μM (IC50) References [1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 892.5±65.0 °C at 760 mmHg Melting Point 242-244℃ Molecular Formula C21H18O12 Molecular Weight 462.360 Flash Point 315.2±27.8 °C Exact Mass 462.079834 PSA 207.35000 LogP -0.25 Vapour Pressure 0.0±0.3 mmHg at 25°C Index of Refraction 1.764 InChIKey VSUOKLTVXQRUSG-ZFORQUDYSA-N SMILES O=C(O)C1OC(Oc2cc(O)c3c(=O)cc(-c4ccc(O)c(O)c4)oc3c2)C(O)C(O)C1O Storage condition ?20°C |
| Use of | Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. Properties Name luteolin 7-O-β-D-glucosiduronic acid Synonym More Synonyms Luteolin-7-O-glucuronide Biological Activity Description Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. Related Catalog Research Areas >> Others Natural Products >> Flavonoids MMP-1:17.63 μM (IC50) MMP-3:7.99 μM (IC50) MMP-8:11.42 μM (IC50) MMP-9:12.85 μM (IC50) MMP13:0.03 μM (IC50) References [1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. Chemical & Physical Properties Molecular Formula C21H18O12 Exact Mass 462.079834 PSA 207.35000 LogP -0.25 Index of Refraction 1.764 InChIKey VSUOKLTVXQRUSG-ZFORQUDYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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