CAS Number57-96-5
Synonymssulphinpyrazone; Diphenylpyrazone; Sulfinpyrazon; Anturane; Sulfoxyphenylpyrazolidine; EINECS 200-357-4; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-1H-pyrazol-3,5(2H,4H)-dion; Enturan; Anturano; Enturen; ulfinpyrazone; Anturan; MFCD00057279; Sulfinpyrazone; 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione; Anturidin; Anturanil; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione; (±)-Sulfinpyrazone
Molecular FormulaC23H20N2O3S
Molecular Weight404.48
Purity≥99%
Density1.4±0.1 g/cm3
Boiling Point590.8±42.0 °C at 760 mmHg
Melting Point>300 °C(lit.)
AppearanceSolid;White to Light yellow powder to crystal
EINECS200-357-4
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57-96-5 |
| Catalog No. | 2A-9008933 |
| Chinese Name | 苯磺保泰松 |
| Synonyms | sulphinpyrazone; Diphenylpyrazone; Sulfinpyrazon; Anturane; Sulfoxyphenylpyrazolidine; EINECS 200-357-4; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-1H-pyrazol-3,5(2H,4H)-dion; Enturan; Anturano; Enturen; ulfinpyrazone; Anturan; MFCD00057279; Sulfinpyrazone; 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione; Anturidin; Anturanil; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione; (±)-Sulfinpyrazone |
| Molecular Formula | C23H20N2O3S |
| Molecular Weight | 404.48 |
| Purity | ≥99 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 590.8±42.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Appearance | Solid;White to Light yellow powder to crystal |
| Water Solubility | soluble |
| Storage Condition | 2-8°C |
| Application | Sulfinpyrazone (G-28315) is an orally active uricosuric agent for the treatment of chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects. |
| EINECS | 200-357-4 |
| HTC | 2933990090 |
| PubChem ID | 329824625 |
| MDL Number | MFCD00057279 |
| SMILES | O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4 |
| InChI | 1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2 |
| InChI Key | MBGGBVCUIVRRBF-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/8933_1_57_96_5.pdf |
| Bioactivity | Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Sulfinpyrazone (G-28315) stimulates fibrinolytic activity[2]. In Vivo In rats with kaolin-induced paw oedema, Sulfinpyrazone (G-28315) is able to restore the markedly prolonged euglobulin clot lysis time in an oral dose of 30 mg/kg. Beside these effects, Sulfinpyrazone protects rabbits from arachidonate-induced sudden death after a single oral dose of 10-30 mg/kg[2]. References [1]. Margulies EH, White AM, Sherry S. Sulfinpyrazone: a review of its pharmacological properties and therapeutic use. Drugs. 1980;20(3):179‐197. [2]. Rüegg M. Antithrombotic effects of sulfinpyrazone in animals: influence on fibrinolysis and sodium arachidonate-induced pulmonary embolism. Pharmacology. 1976;14(6):522‐536. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 590.8±42.0 °C at 760 mmHg Melting Point >300 °C(lit.) Molecular Formula C23H20N2O3S Molecular Weight 404.482 Flash Point 311.1±27.9 °C Exact Mass 404.119476 PSA 76.90000 LogP 2.30 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.717 InChIKey MBGGBVCUIVRRBF-UHFFFAOYSA-N SMILES O=C1C(CCS(=O)c2ccccc2)C(=O)N(c2ccccc2)N1c1ccccc1 Storage condition 2-8°C Water Solubility soluble |
| Use of | Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects[1][2]. Properties Articles37 Name sulfinpyrazone Synonym More Synonyms (±)-Sulfinpyrazone Biological Activity Description Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Sulfinpyrazone (G-28315) stimulates fibrinolytic activity[2]. References [1]. Margulies EH, White AM, Sherry S. Sulfinpyrazone: a review of its pharmacological properties and therapeutic use. Drugs. 1980;20(3):179‐197. [2]. Rüegg M. Antithrombotic effects of sulfinpyrazone in animals: influence on fibrinolysis and sodium arachidonate-induced pulmonary embolism. Pharmacology. 1976;14(6):522‐536. Chemical & Physical Properties Molecular Formula C23H20N2O3S Exact Mass 404.119476 PSA 76.90000 Index of Refraction 1.717 InChIKey MBGGBVCUIVRRBF-UHFFFAOYSA-N Water Solubility soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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