CAS Number57260-73-8
SynonymsCarbamic acid, N-(2-aminoethyl)-, 1,1-dimethylethyl ester; N-tert-Boc-ethylenediamine; tert-butyl-(2-aminoethyl)carbamat; tert-butyl (2-aminoethyl)carbamate; 2-Methyl-2-propanyl (2-aminoethyl)carbamate; tert-butyl N-(2-aminoethyl)carbamate; MFCD00191871; N-(tert-Butoxycarbonyl)-1,2-diaminoethane
Molecular Formula(CH3)3COCONHCH2CH2NH2
Molecular Weight160.21
Purity≥98.0 (NT)%
Density1.0±0.1 g/cm3
Boiling Point72-80 °C/0.1 mmHg (lit.)
AppearanceColorless to light yellow
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57260-73-8 |
| Catalog No. | 2A-9008607 |
| Chinese Name | N-叔丁氧羰基-1,2-乙二胺 |
| Synonyms | Carbamic acid, N-(2-aminoethyl)-, 1,1-dimethylethyl ester; N-tert-Boc-ethylenediamine; tert-butyl-(2-aminoethyl)carbamat; tert-butyl (2-aminoethyl)carbamate; 2-Methyl-2-propanyl (2-aminoethyl)carbamate; tert-butyl N-(2-aminoethyl)carbamate; MFCD00191871; N-(tert-Butoxycarbonyl)-1,2-diaminoethane |
| Molecular Formula | (CH3)3COCONHCH2CH2NH2 |
| Molecular Weight | 160.21 |
| Purity | ≥98.0 (NT) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 72-80 °C/0.1 mmHg (lit.) |
| Appearance | Colorless to light yellow |
| Storage Condition | Keep receptacle sealed Store in a compact containe |
| Packaging | III |
| Application | PROTAC Linker 22 is a PROTAC connection bridge, belonging to the alkyl chain category. PROTAC Linker 22 can be used to synthesize a range of PROTAC molecules. PROTAC molecules contain two different li |
| HTC | 2924199090 |
| UN(IATA) | UN 2735 |
| PubChem ID | 57647392 |
| MDL Number | MFCD00191871 |
| SMILES | NCCNC(OC(C)(C)C)=O |
| InChI | 1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10) |
| InChI Key | AOCSUUGBCMTKJH-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1932330 |
| NACRES Code | NA.22 |
| UNSPSC | 12352116 |
| Hazard Symbols | 8 |
| Risk Codes | R34 |
| Safety Description | S26;S36/37/39;S45 |
| MSDS | msds/8607_2_57260_73_8.pdf |
| Bioactivity | PROTAC Linker 22 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 22 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target Alkyl-Chain References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 252.8±23.0 °C at 760 mmHg Molecular Formula C7H16N2O2 Molecular Weight 160.214 Flash Point 106.7±22.6 °C Exact Mass 160.121185 PSA 64.35000 LogP 0.54 Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.454 InChIKey AOCSUUGBCMTKJH-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCN Storage condition Refrigerator (+4°C) |
| Use of | Properties Name N-Boc-Ethylenediamine Synonym More Synonyms N-Boc-Ethylenediamine Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl-Chain References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C7H16N2O2 Exact Mass 160.121185 PSA 64.35000 Index of Refraction 1.454 InChIKey AOCSUUGBCMTKJH-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCN |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2735 International Dangerous Regulations for sea transport: 2735 International Dangerous Regulations for air transport: 2735 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-ethylenediamine) IMDG Code: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-ethylenediamine) International air transport hazard regulations: Amines, liquid, corrosive, n.o.s. (N-Boc-ethylenediamine) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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