CAS Number5813-86-5
Synonyms3-Methoxybenzamide; MFCD00007986; 3-Methoxy-benzoesaeure-amid; 3-Methoxy-benzamid; 3-methoxy-benzoic acid amide; m-anisamide; Benzamide,3-methoxy; 3-Methoxy-benzamide; EINECS 227-379-7; 3-Methoxyphenylformamide; m-Methoxybenzamide
Molecular FormulaCH3OC6H4CONH2
Molecular Weight151.16
Purity97%
Density1.1±0.1 g/cm3
Boiling Point280.0±23.0 °C at 760 mmHg
Melting Point132.5-135.5 °C (lit.)
EINECS227-379-7
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5813-86-5 |
| Catalog No. | 2A-9085113 |
| Chinese Name | 3-甲氧基苯甲酰胺 |
| Synonyms | 3-Methoxybenzamide; MFCD00007986; 3-Methoxy-benzoesaeure-amid; 3-Methoxy-benzamid; 3-methoxy-benzoic acid amide; m-anisamide; Benzamide,3-methoxy; 3-Methoxy-benzamide; EINECS 227-379-7; 3-Methoxyphenylformamide; m-Methoxybenzamide |
| Molecular Formula | CH3OC6H4CONH2 |
| Molecular Weight | 151.16 |
| Purity | 97 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 280.0±23.0 °C at 760 mmHg |
| Melting Point | 132.5-135.5 °C (lit.) |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | 3-Methoxybenzamide (3-MBA) is an inhibitor of ADP-ribosyltransferases (ADPRTs) and PARP, inhibiting cell division of Bacillus subtilis, leading to eventual cell lysis. 3-Methoxybenzamide (3-MBA) promo |
| EINECS | 227-379-7 |
| HTC | 2924299090 |
| PubChem ID | 24896467 |
| MDL Number | MFCD00007986 |
| SMILES | COc1cccc(c1)C(N)=O |
| InChI | 1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10) |
| InChI Key | VKPLPDIMEREJJF-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2206857 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/85113_1_5813_86_5.pdf |
| Bioactivity | 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP In Vitro 3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation[1]. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants[2]. Cell Viability Assay[1] Cell Line: ftsZ mutant strains. Concentration: 0-30 mM. Incubation Time: 30℃ overnight. Result: Changes directly or indirectly the ability of ftsZ to bind or hydrolyze the guanine nucleotide, ultimately leading to the inhibition of Zring formation. References [1]. Y Ohashi, et al. The lethal effect of a benzamide derivative, 3-methoxybenzamide, can be suppressed by mutations within a cell division gene, ftsZ, in Bacillus subtilis. J Bacteriol. 1999 Feb;181(4):1348-51. [2]. Venkateswari J. Chetty, et al. Poly (ADP-ribose) polymerase inhibitor 3-methoxybenzamide enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). In Vitro Cellular & Developmental Biology - Plant (2020). Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 280.0±23.0 °C at 760 mmHg Melting Point 132.5-135.5 °C(lit.) Molecular Formula C8H9NO2 Molecular Weight 151.163 Flash Point 146.8±18.9 °C Exact Mass 151.063324 PSA 52.32000 LogP 0.85 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.546 InChIKey VKPLPDIMEREJJF-UHFFFAOYSA-N SMILES COc1cccc(C(N)=O)c1 |
| Use of | 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2]. Properties Articles25 Name 3-methoxybenzamide Synonym More Synonyms 3-Methoxybenzamide Biological Activity Description 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP References [1]. Y Ohashi, et al. The lethal effect of a benzamide derivative, 3-methoxybenzamide, can be suppressed by mutations within a cell division gene, ftsZ, in Bacillus subtilis. J Bacteriol. 1999 Feb;181(4):1348-51. [2]. Venkateswari J. Chetty, et al. Poly (ADP-ribose) polymerase inhibitor 3-methoxybenzamide enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). In Vitro Cellular & Developmental Biology - Plant (2020). Chemical & Physical Properties Molecular Formula C8H9NO2 Exact Mass 151.063324 PSA 52.32000 Index of Refraction 1.546 InChIKey VKPLPDIMEREJJF-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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