
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 15793-40-5 |
| Catalog No. | 2A-9084321 |
| Chinese Name | 特罗地林 |
| Synonyms | RS-terodiline; Terodilina; Bicor; Terodiline; 2-tert-Butylamino-4,4-diphenylbutan; Terodilinum; RARECHEM AN KC 0196 |
| Molecular Formula | C20H27N |
| Molecular Weight | 281.44 |
| Density | 0.956g/cm3 |
| Boiling Point | 390.9ºC at 760mmHg |
| Application | Trodiline is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atrium (M2), bladder (M3), and ileum muscle (M3), respectively. Te |
| HTC | 2921499090 |
| MDL Number | C20H27N |
| SMILES | CC(CC(c1ccccc1)c1ccccc1)NC(C)(C)C |
| InChI | InChI=1S/C20H27N.ClH/c1-16(21-20(2,3)4)15-19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,16,19,21H,15H2,1-4H3;1H |
| InChI Key | UISARWKNNNHPGI-UHFFFAOYSA-N |
| MSDS | msds/84321_1_15793_40_5.pdf |
| Use of | Terodiline is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline also is a Ca2+ blocker. Terodiline acts as a treatment for urinary frequency and urge incontinence[1]. Properties Name 1-methyl-3,3-diphenylpropylamine Synonym More Synonyms Terodiline Biological Activity Description Terodiline is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline also is a Ca2+ blocker. Terodiline acts as a treatment for urinary frequency and urge incontinence[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease mAChR[1] Ca2+ channel[1] References [1]. Noronha-Blob L, et al. (±)-Terodiline: an M1-selective muscarinic receptor antagonist. In vivo effects at muscarinic receptors mediating urinary bladder contraction, mydriasis and salivary secretion. Eur J Pharmacol. 1991 Aug 29;201(2-3):135-42. Chemical & Physical Properties Molecular Formula C20H27N Exact Mass 225.15200 PSA 26.02000 LogP 4.25610 Index of Refraction 1.534 InChIKey UISARWKNNNHPGI-UHFFFAOYSA-N Safety Information HS Code 2921499090 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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