| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2140-29-6 |
| Catalog No. | 2A-9083254 |
| Chinese Name | A-葡糖-A-葡糖苷 |
| Synonyms | KOJIBIOSE; Glc1-|A-2Gal |
| Molecular Formula | C12H22O11 |
| Molecular Weight | 342.30 |
| Purity | ≥98 (HPLC) |
| Density | 1.68g/cm3 |
| Boiling Point | 783.7ºC at 760mmHg |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | Kojibiose is an orally active prebiotic disaccharide that can specifically inhibit the activity of α-glucosidase I. Kobiose is a proliferation factor for bifidobacteria, lactobacilli and eubacteria. K |
| PubChem ID | 329817148 |
| MDL Number | MFCD00214308 |
| SMILES | OCC(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C=O |
| InChI | 1S/C12H22O11/c13-1-4(16)7(17)8(18)5(2-14)22-12-11(21)10(20)9(19)6(3-15)23-12/h2,4-13,15-21H,1,3H2 |
| InChI Key | PZDOWFGHCNHPQD-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352201 |
| Hazard Symbols | transportation |
| MSDS | msds/83254_1_2140_29_6.pdf |
| Bioactivity | Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2]. Related Catalog Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease In Vivo Kobiose (0.5 %; w/w daily dietary intake; for 20 days) significantly improves the severity of hepatic changes induced by eicosanoids (ARa; 0.3 mg daily in the diet; for 20 days) [1]. Animal Model: Female Wistar albino rats, aged 3 weeks with Streptozotocin (STZ; HY-13753) two doses of 25 mg/kg per d with a time lapse of 24 h[1] Dosage: 0.5%, w/w Administration: Diet; daily for 20 d Result: Significantly improved the severity of arachidic acid (ARa; 0.3 mg daily for 20 d)-induced hepatic alterations. Significantly increased expression values of PPAR α in comparison with those fed only ARa, suggesting an increased fatty acid metabolism. Showed reduced LPC and PS values than did animals fed only ARa. References [1]. José Moisés Laparra, et al. Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats. Br J Nutr. 2015 Nov 14;114(9):1395-402. [2]. Miaomiao Wang, et al. Cloning and expression of the sucrose phosphorylase gene in Bacillus subtilis and synthesis of kojibiose using the recombinant enzyme. Microb Cell Fact. 2018 Feb 15;17(1):23. Chemical & Physical Properties Density 1.68g/cm3 Boiling Point 783.7ºC at 760mmHg Molecular Formula C12H22O11 Molecular Weight 342.29600 Flash Point 292.1ºC Exact Mass 342.11600 PSA 189.53000 Vapor Pressure 0mmHg at 25°C Index of Refraction 1.652 InChIKey PZDOWFGHCNHPQD-OQPGPFOOSA-N SMILES O=CC(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C(O)CO Storage condition -20°C |
| Use of | Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2]. Properties Articles24 Name kojibiose Synonym More Synonyms Kojibiose Biological Activity Description Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2]. Related Catalog Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease References [1]. José Moisés Laparra, et al. Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats. Br J Nutr. 2015 Nov 14;114(9):1395-402. [2]. Miaomiao Wang, et al. Cloning and expression of the sucrose phosphorylase gene in Bacillus subtilis and synthesis of kojibiose using the recombinant enzyme. Microb Cell Fact. 2018 Feb 15;17(1):23. Chemical & Physical Properties Molecular Formula C12H22O11 Exact Mass 342.11600 PSA 189.53000 Index of Refraction 1.652 InChIKey PZDOWFGHCNHPQD-OQPGPFOOSA-N SMILES O=CC(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C(O)CO |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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