CAS Number7730-20-3
SynonymsEINECS 231-788-6; 2-Amino-3-(6-fluoro-1H-indol-3-yl)propanoic acid; MFCD00005653
Molecular FormulaC11H11O2N2F1
Molecular Weight222.22
Density1.4±0.1 g/cm3
Boiling Point450.7±45.0 °C at 760 mmHg
Melting Point280-285 °C (dec.)(lit.)
Appearanceoff-white powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7730-20-3 |
| Catalog No. | 2A-9082956 |
| Chinese Name | 6-氟-DL-色氨酸 |
| Synonyms | EINECS 231-788-6; 2-Amino-3-(6-fluoro-1H-indol-3-yl)propanoic acid; MFCD00005653 |
| Molecular Formula | C11H11O2N2F1 |
| Molecular Weight | 222.22 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 450.7±45.0 °C at 760 mmHg |
| Melting Point | 280-285 °C (dec.)(lit.) |
| Appearance | off-white powder |
| Storage Condition | -20℃ |
| Application | 6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produces transient sleep disruption in rats with long-term implantation of electroencephalogram recording electrodes [1]. |
| HTC | 2933990090 |
| MDL Number | MFCD00005653 |
| SMILES | NC(Cc1c[nH]c2cc(F)ccc12)C(=O)O |
| InChI | InChI=1S/C11H11FN2O2/c12-7-1-2-8-6(3-9(13)11(15)16)5-14-10(8)4-7/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1 |
| InChI Key | YMEXGEAJNZRQEH-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/82956_1_7730_20_3.pdf |
| Bioactivity | 6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Tryptophan Hydroxylase Research Areas >> Neurological Disease References [1]. Miwa S, et al. Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. J Neurochem. 1987 May;48(5):1577-80. [2]. D Sugden, et al. Changes in the rat sleep-wake cycle produced by DL-6-fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase. Psychopharmacology (Berl). 1981;74(4):369-73. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 450.7±45.0 °C at 760 mmHg Melting Point 280-285 °C (dec.)(lit.) Molecular Formula C11H11FN2O2 Molecular Weight 222.216 Flash Point 226.4±28.7 °C Exact Mass 222.080460 PSA 79.11000 LogP 1.09 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.673 InChIKey YMEXGEAJNZRQEH-UHFFFAOYSA-N SMILES NC(Cc1c[nH]c2cc(F)ccc12)C(=O)O Storage condition −20°C |
| Use of | 6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1]. Properties Articles29 Name 6-Fluoro-DL-tryptophan Synonym More Synonyms Description 6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Tryptophan Hydroxylase Research Areas >> Neurological Disease References [1]. Miwa S, et al. Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. J Neurochem. 1987 May;48(5):1577-80. [2]. D Sugden, et al. Changes in the rat sleep-wake cycle produced by DL-6-fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase. Psychopharmacology (Berl). 1981;74(4):369-73. Chemical & Physical Properties Molecular Formula C11H11FN2O2 Exact Mass 222.080460 PSA 79.11000 Index of Refraction 1.673 InChIKey YMEXGEAJNZRQEH-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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